diff --git a/llvm/include/llvm/Transforms/Instrumentation/InstrProfiling.h b/llvm/include/llvm/Transforms/Instrumentation/InstrProfiling.h
--- a/llvm/include/llvm/Transforms/Instrumentation/InstrProfiling.h
+++ b/llvm/include/llvm/Transforms/Instrumentation/InstrProfiling.h
@@ -57,6 +57,9 @@
     }
   };
   DenseMap<GlobalVariable *, PerFunctionProfileData> ProfileDataMap;
+  /// If runtime relocation is enabled, this maps functions to the load
+  /// instruction that produces the profile relocation bias.
+  DenseMap<const Function *, LoadInst *> FunctionToProfileBiasLI;
   std::vector<GlobalValue *> CompilerUsedVars;
   std::vector<GlobalValue *> UsedVars;
   std::vector<GlobalVariable *> ReferencedNames;
diff --git a/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp b/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp
--- a/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp
+++ b/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp
@@ -700,10 +700,9 @@
     Type *Int64Ty = Type::getInt64Ty(M->getContext());
     Type *Int64PtrTy = Type::getInt64PtrTy(M->getContext());
     Function *Fn = Inc->getParent()->getParent();
-    Instruction &I = Fn->getEntryBlock().front();
-    LoadInst *LI = dyn_cast<LoadInst>(&I);
-    if (!LI) {
-      IRBuilder<> Builder(&I);
+    auto *&BiasLI = FunctionToProfileBiasLI[Fn];
+    if (!BiasLI) {
+      IRBuilder<> Builder(&Fn->getEntryBlock().front());
       GlobalVariable *Bias =
           M->getGlobalVariable(getInstrProfCounterBiasVarName());
       if (!Bias) {
@@ -721,9 +720,10 @@
         if (TT.supportsCOMDAT())
           Bias->setComdat(M->getOrInsertComdat(Bias->getName()));
       }
-      LI = Builder.CreateLoad(Int64Ty, Bias);
+      BiasLI = Builder.CreateLoad(Int64Ty, Bias);
     }
-    auto *Add = Builder.CreateAdd(Builder.CreatePtrToInt(Addr, Int64Ty), LI);
+    auto *Add =
+        Builder.CreateAdd(Builder.CreatePtrToInt(Addr, Int64Ty), BiasLI);
     Addr = Builder.CreateIntToPtr(Add, Int64PtrTy);
   }