diff --git a/llvm/lib/Transforms/InstCombine/InstCombineAndOrXor.cpp b/llvm/lib/Transforms/InstCombine/InstCombineAndOrXor.cpp
--- a/llvm/lib/Transforms/InstCombine/InstCombineAndOrXor.cpp
+++ b/llvm/lib/Transforms/InstCombine/InstCombineAndOrXor.cpp
@@ -2796,6 +2796,26 @@
   if (match(Op0, m_And(m_Or(m_Specific(Op1), m_Value(C)), m_Value(A))))
     return BinaryOperator::CreateOr(Op1, Builder.CreateAnd(A, C));
 
+  // (~(A | B) & C) | (~(A | C) & B) --> (B ^ C) & ~A
+  // TODO: One use checks are conservative. We have 7 operations in the source
+  //       expression and 3 in the target. We could allow 3 multiple used values
+  //       in RHS and LHS combined, but there is no common infrastructure to
+  //       conveniently do so no.
+  if (match(Op0, m_OneUse(m_c_And(m_OneUse(m_Not(m_Or(m_Value(A), m_Value(B)))),
+                                  m_Value(C))))) {
+    if (match(Op1, m_OneUse(m_c_And(
+                       m_OneUse(m_Not(m_c_Or(m_Specific(A), m_Specific(C)))),
+                       m_Specific(B)))))
+      return BinaryOperator::CreateAnd(Builder.CreateXor(B, C),
+                                       Builder.CreateNot(A));
+
+    if (match(Op1, m_OneUse(m_c_And(
+                       m_OneUse(m_Not(m_c_Or(m_Specific(B), m_Specific(C)))),
+                       m_Specific(A)))))
+      return BinaryOperator::CreateAnd(Builder.CreateXor(A, C),
+                                       Builder.CreateNot(B));
+  }
+
   if (Instruction *DeMorgan = matchDeMorgansLaws(I, Builder))
     return DeMorgan;
 
diff --git a/llvm/test/Transforms/InstCombine/and-xor-or.ll b/llvm/test/Transforms/InstCombine/and-xor-or.ll
--- a/llvm/test/Transforms/InstCombine/and-xor-or.ll
+++ b/llvm/test/Transforms/InstCombine/and-xor-or.ll
@@ -703,13 +703,9 @@
 
 define i32 @or_not_and(i32 %a, i32 %b, i32 %c) {
 ; CHECK-LABEL: @or_not_and(
-; CHECK-NEXT:    [[OR1:%.*]] = or i32 [[A:%.*]], [[B:%.*]]
-; CHECK-NEXT:    [[NOT1:%.*]] = xor i32 [[OR1]], -1
-; CHECK-NEXT:    [[AND1:%.*]] = and i32 [[NOT1]], [[C:%.*]]
-; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[A]], [[C]]
-; CHECK-NEXT:    [[NOT2:%.*]] = xor i32 [[OR2]], -1
-; CHECK-NEXT:    [[AND2:%.*]] = and i32 [[NOT2]], [[B]]
-; CHECK-NEXT:    [[OR3:%.*]] = or i32 [[AND1]], [[AND2]]
+; CHECK-NEXT:    [[TMP1:%.*]] = xor i32 [[B:%.*]], [[C:%.*]]
+; CHECK-NEXT:    [[TMP2:%.*]] = xor i32 [[A:%.*]], -1
+; CHECK-NEXT:    [[OR3:%.*]] = and i32 [[TMP1]], [[TMP2]]
 ; CHECK-NEXT:    ret i32 [[OR3]]
 ;
   %or1 = or i32 %a, %b
@@ -725,13 +721,9 @@
 define i32 @or_not_and_commute1(i32 %a, i32 %b0, i32 %c) {
 ; CHECK-LABEL: @or_not_and_commute1(
 ; CHECK-NEXT:    [[B:%.*]] = sdiv i32 42, [[B0:%.*]]
-; CHECK-NEXT:    [[OR1:%.*]] = or i32 [[B]], [[A:%.*]]
-; CHECK-NEXT:    [[NOT1:%.*]] = xor i32 [[OR1]], -1
-; CHECK-NEXT:    [[AND1:%.*]] = and i32 [[NOT1]], [[C:%.*]]
-; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[A]], [[C]]
-; CHECK-NEXT:    [[NOT2:%.*]] = xor i32 [[OR2]], -1
-; CHECK-NEXT:    [[AND2:%.*]] = and i32 [[B]], [[NOT2]]
-; CHECK-NEXT:    [[OR3:%.*]] = or i32 [[AND1]], [[AND2]]
+; CHECK-NEXT:    [[TMP1:%.*]] = xor i32 [[B]], [[C:%.*]]
+; CHECK-NEXT:    [[TMP2:%.*]] = xor i32 [[A:%.*]], -1
+; CHECK-NEXT:    [[OR3:%.*]] = and i32 [[TMP1]], [[TMP2]]
 ; CHECK-NEXT:    ret i32 [[OR3]]
 ;
   %b = sdiv i32 42, %b0 ; thwart complexity-based canonicalization
@@ -748,13 +740,9 @@
 define i32 @or_not_and_commute2(i32 %a, i32 %b0, i32 %c) {
 ; CHECK-LABEL: @or_not_and_commute2(
 ; CHECK-NEXT:    [[B:%.*]] = sdiv i32 42, [[B0:%.*]]
-; CHECK-NEXT:    [[OR1:%.*]] = or i32 [[B]], [[A:%.*]]
-; CHECK-NEXT:    [[NOT1:%.*]] = xor i32 [[OR1]], -1
-; CHECK-NEXT:    [[AND1:%.*]] = and i32 [[NOT1]], [[C:%.*]]
-; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[A]], [[C]]
-; CHECK-NEXT:    [[NOT2:%.*]] = xor i32 [[OR2]], -1
-; CHECK-NEXT:    [[AND2:%.*]] = and i32 [[B]], [[NOT2]]
-; CHECK-NEXT:    [[OR3:%.*]] = or i32 [[AND2]], [[AND1]]
+; CHECK-NEXT:    [[TMP1:%.*]] = xor i32 [[B]], [[C:%.*]]
+; CHECK-NEXT:    [[TMP2:%.*]] = xor i32 [[A:%.*]], -1
+; CHECK-NEXT:    [[OR3:%.*]] = and i32 [[TMP1]], [[TMP2]]
 ; CHECK-NEXT:    ret i32 [[OR3]]
 ;
   %b = sdiv i32 42, %b0 ; thwart complexity-based canonicalization
@@ -770,13 +758,9 @@
 
 define i32 @or_not_and_commute3(i32 %a, i32 %b, i32 %c) {
 ; CHECK-LABEL: @or_not_and_commute3(
-; CHECK-NEXT:    [[OR1:%.*]] = or i32 [[B:%.*]], [[A:%.*]]
-; CHECK-NEXT:    [[NOT1:%.*]] = xor i32 [[OR1]], -1
-; CHECK-NEXT:    [[AND1:%.*]] = and i32 [[NOT1]], [[C:%.*]]
-; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[C]], [[A]]
-; CHECK-NEXT:    [[NOT2:%.*]] = xor i32 [[OR2]], -1
-; CHECK-NEXT:    [[AND2:%.*]] = and i32 [[NOT2]], [[B]]
-; CHECK-NEXT:    [[OR3:%.*]] = or i32 [[AND1]], [[AND2]]
+; CHECK-NEXT:    [[TMP1:%.*]] = xor i32 [[B:%.*]], [[C:%.*]]
+; CHECK-NEXT:    [[TMP2:%.*]] = xor i32 [[A:%.*]], -1
+; CHECK-NEXT:    [[OR3:%.*]] = and i32 [[TMP1]], [[TMP2]]
 ; CHECK-NEXT:    ret i32 [[OR3]]
 ;
   %or1 = or i32 %b, %a
@@ -792,13 +776,9 @@
 define i32 @or_not_and_commute4(i32 %a, i32 %b, i32 %c0) {
 ; CHECK-LABEL: @or_not_and_commute4(
 ; CHECK-NEXT:    [[C:%.*]] = sdiv i32 42, [[C0:%.*]]
-; CHECK-NEXT:    [[OR1:%.*]] = or i32 [[A:%.*]], [[B:%.*]]
-; CHECK-NEXT:    [[NOT1:%.*]] = xor i32 [[OR1]], -1
-; CHECK-NEXT:    [[AND1:%.*]] = and i32 [[C]], [[NOT1]]
-; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[C]], [[A]]
-; CHECK-NEXT:    [[NOT2:%.*]] = xor i32 [[OR2]], -1
-; CHECK-NEXT:    [[AND2:%.*]] = and i32 [[NOT2]], [[B]]
-; CHECK-NEXT:    [[OR3:%.*]] = or i32 [[AND1]], [[AND2]]
+; CHECK-NEXT:    [[TMP1:%.*]] = xor i32 [[C]], [[B:%.*]]
+; CHECK-NEXT:    [[TMP2:%.*]] = xor i32 [[A:%.*]], -1
+; CHECK-NEXT:    [[OR3:%.*]] = and i32 [[TMP1]], [[TMP2]]
 ; CHECK-NEXT:    ret i32 [[OR3]]
 ;
   %c = sdiv i32 42, %c0 ; thwart complexity-based canonicalization
@@ -816,13 +796,9 @@
 ; CHECK-LABEL: @or_not_and_commute5(
 ; CHECK-NEXT:    [[A:%.*]] = sdiv i32 42, [[A0:%.*]]
 ; CHECK-NEXT:    [[C:%.*]] = sdiv i32 42, [[C0:%.*]]
-; CHECK-NEXT:    [[OR1:%.*]] = or i32 [[A]], [[B:%.*]]
-; CHECK-NEXT:    [[NOT1:%.*]] = xor i32 [[OR1]], -1
-; CHECK-NEXT:    [[AND1:%.*]] = and i32 [[C]], [[NOT1]]
-; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[A]], [[C]]
-; CHECK-NEXT:    [[NOT2:%.*]] = xor i32 [[OR2]], -1
-; CHECK-NEXT:    [[AND2:%.*]] = and i32 [[NOT2]], [[B]]
-; CHECK-NEXT:    [[OR3:%.*]] = or i32 [[AND1]], [[AND2]]
+; CHECK-NEXT:    [[TMP1:%.*]] = xor i32 [[C]], [[B:%.*]]
+; CHECK-NEXT:    [[TMP2:%.*]] = xor i32 [[A]], -1
+; CHECK-NEXT:    [[OR3:%.*]] = and i32 [[TMP1]], [[TMP2]]
 ; CHECK-NEXT:    ret i32 [[OR3]]
 ;
   %a = sdiv i32 42, %a0 ; thwart complexity-based canonicalization
@@ -839,13 +815,9 @@
 
 define i32 @or_not_and_commute6(i32 %a, i32 %b, i32 %c) {
 ; CHECK-LABEL: @or_not_and_commute6(
-; CHECK-NEXT:    [[OR1:%.*]] = or i32 [[A:%.*]], [[B:%.*]]
-; CHECK-NEXT:    [[NOT1:%.*]] = xor i32 [[OR1]], -1
-; CHECK-NEXT:    [[AND1:%.*]] = and i32 [[NOT1]], [[C:%.*]]
-; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[C]], [[A]]
-; CHECK-NEXT:    [[NOT2:%.*]] = xor i32 [[OR2]], -1
-; CHECK-NEXT:    [[AND2:%.*]] = and i32 [[NOT2]], [[B]]
-; CHECK-NEXT:    [[OR3:%.*]] = or i32 [[AND1]], [[AND2]]
+; CHECK-NEXT:    [[TMP1:%.*]] = xor i32 [[B:%.*]], [[C:%.*]]
+; CHECK-NEXT:    [[TMP2:%.*]] = xor i32 [[A:%.*]], -1
+; CHECK-NEXT:    [[OR3:%.*]] = and i32 [[TMP1]], [[TMP2]]
 ; CHECK-NEXT:    ret i32 [[OR3]]
 ;
   %or1 = or i32 %a, %b
@@ -860,13 +832,9 @@
 
 define i32 @or_not_and_commute7(i32 %a, i32 %b, i32 %c) {
 ; CHECK-LABEL: @or_not_and_commute7(
-; CHECK-NEXT:    [[OR1:%.*]] = or i32 [[B:%.*]], [[A:%.*]]
-; CHECK-NEXT:    [[NOT1:%.*]] = xor i32 [[OR1]], -1
-; CHECK-NEXT:    [[AND1:%.*]] = and i32 [[NOT1]], [[C:%.*]]
-; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[A]], [[C]]
-; CHECK-NEXT:    [[NOT2:%.*]] = xor i32 [[OR2]], -1
-; CHECK-NEXT:    [[AND2:%.*]] = and i32 [[NOT2]], [[B]]
-; CHECK-NEXT:    [[OR3:%.*]] = or i32 [[AND1]], [[AND2]]
+; CHECK-NEXT:    [[TMP1:%.*]] = xor i32 [[B:%.*]], [[C:%.*]]
+; CHECK-NEXT:    [[TMP2:%.*]] = xor i32 [[A:%.*]], -1
+; CHECK-NEXT:    [[OR3:%.*]] = and i32 [[TMP1]], [[TMP2]]
 ; CHECK-NEXT:    ret i32 [[OR3]]
 ;
   %or1 = or i32 %b, %a
@@ -883,13 +851,9 @@
 ; CHECK-LABEL: @or_not_and_commute8(
 ; CHECK-NEXT:    [[A:%.*]] = sdiv i32 42, [[A0:%.*]]
 ; CHECK-NEXT:    [[B:%.*]] = sdiv i32 42, [[B0:%.*]]
-; CHECK-NEXT:    [[OR1:%.*]] = or i32 [[A]], [[B]]
-; CHECK-NEXT:    [[NOT1:%.*]] = xor i32 [[OR1]], -1
-; CHECK-NEXT:    [[AND1:%.*]] = and i32 [[NOT1]], [[C:%.*]]
-; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[A]], [[C]]
-; CHECK-NEXT:    [[NOT2:%.*]] = xor i32 [[OR2]], -1
-; CHECK-NEXT:    [[AND2:%.*]] = and i32 [[B]], [[NOT2]]
-; CHECK-NEXT:    [[OR3:%.*]] = or i32 [[AND1]], [[AND2]]
+; CHECK-NEXT:    [[TMP1:%.*]] = xor i32 [[B]], [[C:%.*]]
+; CHECK-NEXT:    [[TMP2:%.*]] = xor i32 [[A]], -1
+; CHECK-NEXT:    [[OR3:%.*]] = and i32 [[TMP1]], [[TMP2]]
 ; CHECK-NEXT:    ret i32 [[OR3]]
 ;
   %a = sdiv i32 42, %a0 ; thwart complexity-based canonicalization
@@ -909,13 +873,9 @@
 ; CHECK-NEXT:    [[A:%.*]] = sdiv i32 42, [[A0:%.*]]
 ; CHECK-NEXT:    [[B:%.*]] = sdiv i32 42, [[B0:%.*]]
 ; CHECK-NEXT:    [[C:%.*]] = sdiv i32 42, [[C0:%.*]]
-; CHECK-NEXT:    [[OR1:%.*]] = or i32 [[A]], [[B]]
-; CHECK-NEXT:    [[NOT1:%.*]] = xor i32 [[OR1]], -1
-; CHECK-NEXT:    [[AND1:%.*]] = and i32 [[C]], [[NOT1]]
-; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[A]], [[C]]
-; CHECK-NEXT:    [[NOT2:%.*]] = xor i32 [[OR2]], -1
-; CHECK-NEXT:    [[AND2:%.*]] = and i32 [[B]], [[NOT2]]
-; CHECK-NEXT:    [[OR3:%.*]] = or i32 [[AND1]], [[AND2]]
+; CHECK-NEXT:    [[TMP1:%.*]] = xor i32 [[B]], [[C]]
+; CHECK-NEXT:    [[TMP2:%.*]] = xor i32 [[A]], -1
+; CHECK-NEXT:    [[OR3:%.*]] = and i32 [[TMP1]], [[TMP2]]
 ; CHECK-NEXT:    ret i32 [[OR3]]
 ;
   %a = sdiv i32 42, %a0 ; thwart complexity-based canonicalization
@@ -1026,12 +986,9 @@
 define i32 @or_not_and_extra_or_use1(i32 %a, i32 %b, i32 %c) {
 ; CHECK-LABEL: @or_not_and_extra_or_use1(
 ; CHECK-NEXT:    [[OR1:%.*]] = or i32 [[A:%.*]], [[B:%.*]]
-; CHECK-NEXT:    [[NOT1:%.*]] = xor i32 [[OR1]], -1
-; CHECK-NEXT:    [[AND1:%.*]] = and i32 [[NOT1]], [[C:%.*]]
-; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[A]], [[C]]
-; CHECK-NEXT:    [[NOT2:%.*]] = xor i32 [[OR2]], -1
-; CHECK-NEXT:    [[AND2:%.*]] = and i32 [[NOT2]], [[B]]
-; CHECK-NEXT:    [[OR3:%.*]] = or i32 [[AND1]], [[AND2]]
+; CHECK-NEXT:    [[TMP1:%.*]] = xor i32 [[B]], [[C:%.*]]
+; CHECK-NEXT:    [[TMP2:%.*]] = xor i32 [[A]], -1
+; CHECK-NEXT:    [[OR3:%.*]] = and i32 [[TMP1]], [[TMP2]]
 ; CHECK-NEXT:    call void @use(i32 [[OR1]])
 ; CHECK-NEXT:    ret i32 [[OR3]]
 ;
@@ -1048,13 +1005,10 @@
 
 define i32 @or_not_and_extra_or_use2(i32 %a, i32 %b, i32 %c) {
 ; CHECK-LABEL: @or_not_and_extra_or_use2(
-; CHECK-NEXT:    [[OR1:%.*]] = or i32 [[A:%.*]], [[B:%.*]]
-; CHECK-NEXT:    [[NOT1:%.*]] = xor i32 [[OR1]], -1
-; CHECK-NEXT:    [[AND1:%.*]] = and i32 [[NOT1]], [[C:%.*]]
-; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[A]], [[C]]
-; CHECK-NEXT:    [[NOT2:%.*]] = xor i32 [[OR2]], -1
-; CHECK-NEXT:    [[AND2:%.*]] = and i32 [[NOT2]], [[B]]
-; CHECK-NEXT:    [[OR3:%.*]] = or i32 [[AND1]], [[AND2]]
+; CHECK-NEXT:    [[OR2:%.*]] = or i32 [[A:%.*]], [[C:%.*]]
+; CHECK-NEXT:    [[TMP1:%.*]] = xor i32 [[B:%.*]], [[C]]
+; CHECK-NEXT:    [[TMP2:%.*]] = xor i32 [[A]], -1
+; CHECK-NEXT:    [[OR3:%.*]] = and i32 [[TMP1]], [[TMP2]]
 ; CHECK-NEXT:    call void @use(i32 [[OR2]])
 ; CHECK-NEXT:    ret i32 [[OR3]]
 ;