diff --git a/openmp/libomptarget/CMakeLists.txt b/openmp/libomptarget/CMakeLists.txt
--- a/openmp/libomptarget/CMakeLists.txt
+++ b/openmp/libomptarget/CMakeLists.txt
@@ -38,10 +38,12 @@
 # This is a list of all the targets that are supported/tested right now.
 set (LIBOMPTARGET_ALL_TARGETS "${LIBOMPTARGET_ALL_TARGETS} aarch64-unknown-linux-gnu")
 set (LIBOMPTARGET_ALL_TARGETS "${LIBOMPTARGET_ALL_TARGETS} amdgcn-amd-amdhsa")
+set (LIBOMPTARGET_ALL_TARGETS "${LIBOMPTARGET_ALL_TARGETS} amdgcn-amd-amdhsa-newRTL")
 set (LIBOMPTARGET_ALL_TARGETS "${LIBOMPTARGET_ALL_TARGETS} powerpc64le-ibm-linux-gnu")
 set (LIBOMPTARGET_ALL_TARGETS "${LIBOMPTARGET_ALL_TARGETS} powerpc64-ibm-linux-gnu")
 set (LIBOMPTARGET_ALL_TARGETS "${LIBOMPTARGET_ALL_TARGETS} x86_64-pc-linux-gnu")
 set (LIBOMPTARGET_ALL_TARGETS "${LIBOMPTARGET_ALL_TARGETS} nvptx64-nvidia-cuda")
+set (LIBOMPTARGET_ALL_TARGETS "${LIBOMPTARGET_ALL_TARGETS} nvptx64-nvidia-cuda-newRTL")
 
 # Once the plugins for the different targets are validated, they will be added to
 # the list of supported targets in the current system.
diff --git a/openmp/libomptarget/plugins/amdgpu/CMakeLists.txt b/openmp/libomptarget/plugins/amdgpu/CMakeLists.txt
--- a/openmp/libomptarget/plugins/amdgpu/CMakeLists.txt
+++ b/openmp/libomptarget/plugins/amdgpu/CMakeLists.txt
@@ -122,4 +122,6 @@
 
 # Report to the parent scope that we are building a plugin for amdgpu
 set(LIBOMPTARGET_SYSTEM_TARGETS "${LIBOMPTARGET_SYSTEM_TARGETS} amdgcn-amd-amdhsa" PARENT_SCOPE)
+# new DeviceRTL does not yet compile on amdgpu
+# set(LIBOMPTARGET_SYSTEM_TARGETS "${LIBOMPTARGET_SYSTEM_TARGETS} amdgcn-amd-amdhsa-newRTL" PARENT_SCOPE)
 
diff --git a/openmp/libomptarget/plugins/cuda/CMakeLists.txt b/openmp/libomptarget/plugins/cuda/CMakeLists.txt
--- a/openmp/libomptarget/plugins/cuda/CMakeLists.txt
+++ b/openmp/libomptarget/plugins/cuda/CMakeLists.txt
@@ -66,6 +66,7 @@
 if (LIBOMPTARGET_CAN_LINK_LIBCUDA OR LIBOMPTARGET_FORCE_DLOPEN_LIBCUDA)
   libomptarget_say("Enable tests using CUDA plugin")
   set(LIBOMPTARGET_SYSTEM_TARGETS "${LIBOMPTARGET_SYSTEM_TARGETS} nvptx64-nvidia-cuda" PARENT_SCOPE)
+  set(LIBOMPTARGET_SYSTEM_TARGETS "${LIBOMPTARGET_SYSTEM_TARGETS} nvptx64-nvidia-cuda-newRTL" PARENT_SCOPE)
 else()
   libomptarget_say("Disabling tests using CUDA plugin as cuda may not be available")
 endif()
diff --git a/openmp/libomptarget/test/lit.cfg b/openmp/libomptarget/test/lit.cfg
--- a/openmp/libomptarget/test/lit.cfg
+++ b/openmp/libomptarget/test/lit.cfg
@@ -96,6 +96,8 @@
         config.test_flags += " --libomptarget-amdgcn-bc-path=" + config.library_dir
     if config.libomptarget_current_target.startswith('nvptx'):
         config.test_flags += " --libomptarget-nvptx-bc-path=" + config.library_dir
+    if config.libomptarget_current_target.endswith('-newRTL'):
+        config.test_flags += " -fopenmp-target-new-runtime"
 
 # substitutions
 # - for targets that exist in the system create the actual command.