diff --git a/compiler-rt/lib/msan/msan_interceptors.cpp b/compiler-rt/lib/msan/msan_interceptors.cpp
--- a/compiler-rt/lib/msan/msan_interceptors.cpp
+++ b/compiler-rt/lib/msan/msan_interceptors.cpp
@@ -658,7 +658,8 @@
   return res;
 }
 
-#if SANITIZER_FREEBSD || SANITIZER_NETBSD
+#define SANITIZER_STAT_LINUX (SANITIZER_LINUX && __GLIBC_PREREQ(2, 33))
+#if SANITIZER_FREEBSD || SANITIZER_NETBSD || SANITIZER_STAT_LINUX
 INTERCEPTOR(int, fstat, int fd, void *buf) {
   ENSURE_MSAN_INITED();
   int res = REAL(fstat)(fd, buf);
@@ -666,7 +667,7 @@
     __msan_unpoison(buf, __sanitizer::struct_stat_sz);
   return res;
 }
-#define MSAN_MAYBE_INTERCEPT_FSTAT INTERCEPT_FUNCTION(fstat)
+#define MSAN_MAYBE_INTERCEPT_FSTAT MSAN_INTERCEPT_FUNC(fstat)
 #else
 #define MSAN_MAYBE_INTERCEPT_FSTAT
 #endif
@@ -679,7 +680,7 @@
     __msan_unpoison(buf, __sanitizer::struct_stat_sz);
   return res;
 }
-#define MSAN_MAYBE_INTERCEPT___FXSTAT INTERCEPT_FUNCTION(__fxstat)
+#define MSAN_MAYBE_INTERCEPT___FXSTAT MSAN_INTERCEPT_FUNC(__fxstat)
 #else
 #define MSAN_MAYBE_INTERCEPT___FXSTAT
 #endif
@@ -692,20 +693,24 @@
     __msan_unpoison(buf, __sanitizer::struct_stat64_sz);
   return res;
 }
-#define MSAN_MAYBE_INTERCEPT___FXSTAT64 INTERCEPT_FUNCTION(__fxstat64)
+#define MSAN_MAYBE_INTERCEPT___FXSTAT64 MSAN_INTERCEPT_FUNC(__fxstat64)
 #else
 #define MSAN_MAYBE_INTERCEPT___FXSTAT64
 #endif
 
-#if SANITIZER_FREEBSD || SANITIZER_NETBSD
+#if SANITIZER_FREEBSD || SANITIZER_NETBSD || SANITIZER_STAT_LINUX
 INTERCEPTOR(int, fstatat, int fd, char *pathname, void *buf, int flags) {
   ENSURE_MSAN_INITED();
   int res = REAL(fstatat)(fd, pathname, buf, flags);
   if (!res) __msan_unpoison(buf, __sanitizer::struct_stat_sz);
   return res;
 }
-# define MSAN_INTERCEPT_FSTATAT INTERCEPT_FUNCTION(fstatat)
+# define MSAN_INTERCEPT_FSTATAT MSAN_INTERCEPT_FUNC(fstatat)
 #else
+# define MSAN_INTERCEPT_FSTATAT
+#endif
+
+#if !SANITIZER_FREEBSD && !SANITIZER_NETBSD
 INTERCEPTOR(int, __fxstatat, int magic, int fd, char *pathname, void *buf,
             int flags) {
   ENSURE_MSAN_INITED();
@@ -713,7 +718,9 @@
   if (!res) __msan_unpoison(buf, __sanitizer::struct_stat_sz);
   return res;
 }
-# define MSAN_INTERCEPT_FSTATAT INTERCEPT_FUNCTION(__fxstatat)
+# define MSAN_INTERCEPT___FXSTATAT MSAN_INTERCEPT_FUNC(__fxstatat)
+#else
+# define MSAN_INTERCEPT___FXSTATAT
 #endif
 
 #if !SANITIZER_FREEBSD && !SANITIZER_NETBSD
@@ -724,7 +731,7 @@
   if (!res) __msan_unpoison(buf, __sanitizer::struct_stat64_sz);
   return res;
 }
-#define MSAN_MAYBE_INTERCEPT___FXSTATAT64 INTERCEPT_FUNCTION(__fxstatat64)
+#define MSAN_MAYBE_INTERCEPT___FXSTATAT64 MSAN_INTERCEPT_FUNC(__fxstatat64)
 #else
 #define MSAN_MAYBE_INTERCEPT___FXSTATAT64
 #endif
@@ -1691,6 +1698,7 @@
   MSAN_MAYBE_INTERCEPT_FSTAT;
   MSAN_MAYBE_INTERCEPT___FXSTAT;
   MSAN_INTERCEPT_FSTATAT;
+  MSAN_INTERCEPT___FXSTATAT;
   MSAN_MAYBE_INTERCEPT___FXSTAT64;
   MSAN_MAYBE_INTERCEPT___FXSTATAT64;
   INTERCEPT_FUNCTION(pipe);
diff --git a/compiler-rt/lib/sanitizer_common/sanitizer_platform_interceptors.h b/compiler-rt/lib/sanitizer_common/sanitizer_platform_interceptors.h
--- a/compiler-rt/lib/sanitizer_common/sanitizer_platform_interceptors.h
+++ b/compiler-rt/lib/sanitizer_common/sanitizer_platform_interceptors.h
@@ -460,10 +460,13 @@
 #define SANITIZER_INTERCEPT_SEND_SENDTO SI_POSIX
 #define SANITIZER_INTERCEPT_EVENTFD_READ_WRITE SI_LINUX
 
+#define SI_STAT_LINUX (SI_LINUX && __GLIBC_PREREQ(2, 33))
 #define SANITIZER_INTERCEPT_STAT \
-  (SI_FREEBSD || SI_MAC || SI_ANDROID || SI_NETBSD || SI_SOLARIS)
+  (SI_FREEBSD || SI_MAC || SI_ANDROID || SI_NETBSD || SI_SOLARIS || \
+   SI_STAT_LINUX)
 #define SANITIZER_INTERCEPT_LSTAT (SI_NETBSD || SI_FREEBSD)
-#define SANITIZER_INTERCEPT___XSTAT (!SANITIZER_INTERCEPT_STAT && SI_POSIX)
+#define SANITIZER_INTERCEPT___XSTAT \
+  (!SANITIZER_INTERCEPT_STAT && SI_POSIX) || SI_STAT_LINUX
 #define SANITIZER_INTERCEPT___XSTAT64 SI_LINUX_NOT_ANDROID
 #define SANITIZER_INTERCEPT___LXSTAT SANITIZER_INTERCEPT___XSTAT
 #define SANITIZER_INTERCEPT___LXSTAT64 SI_LINUX_NOT_ANDROID
diff --git a/compiler-rt/test/msan/fstat.cpp b/compiler-rt/test/msan/fstat.cpp
--- a/compiler-rt/test/msan/fstat.cpp
+++ b/compiler-rt/test/msan/fstat.cpp
@@ -1,4 +1,4 @@
-// RUN: %clangxx_msan -O0 %s -o %t && %run %t
+// RUN: %clangxx_msan -O0 -fPIC %s -o %t && %run %t
 
 #include <sys/stat.h>
 #include <stdlib.h>