diff --git a/llvm/lib/Target/X86/X86TargetTransformInfo.cpp b/llvm/lib/Target/X86/X86TargetTransformInfo.cpp
--- a/llvm/lib/Target/X86/X86TargetTransformInfo.cpp
+++ b/llvm/lib/Target/X86/X86TargetTransformInfo.cpp
@@ -5277,6 +5277,7 @@
       {4, MVT::v2i64, 6},  // (load 8i64 and) deinterleave into 4 x 2i64
       {4, MVT::v4i64, 8},  // (load 16i64 and) deinterleave into 4 x 4i64
       {4, MVT::v8i64, 20}, // (load 32i64 and) deinterleave into 4 x 8i64
+      {4, MVT::v16i64, 40}, // (load 64i64 and) deinterleave into 4 x 16i64
 
       {6, MVT::v2i8, 6},   // (load 12i8 and) deinterleave into 6 x 2i8
       {6, MVT::v4i8, 14},  // (load 24i8 and) deinterleave into 6 x 4i8
@@ -5385,6 +5386,7 @@
       {4, MVT::v2i64, 6},  // interleave 4 x 2i64 into 8i64 (and store)
       {4, MVT::v4i64, 8},  // interleave 4 x 4i64 into 16i64 (and store)
       {4, MVT::v8i64, 20}, // interleave 4 x 8i64 into 32i64 (and store)
+      {4, MVT::v16i64, 40}, // interleave 4 x 16i64 into 64i64 (and store)
 
       {6, MVT::v2i8, 7},   // interleave 6 x 2i8 into 12i8 (and store)
       {6, MVT::v4i8, 9},   // interleave 6 x 4i8 into 24i8 (and store)
diff --git a/llvm/test/Analysis/CostModel/X86/interleaved-load-f64-stride-4.ll b/llvm/test/Analysis/CostModel/X86/interleaved-load-f64-stride-4.ll
--- a/llvm/test/Analysis/CostModel/X86/interleaved-load-f64-stride-4.ll
+++ b/llvm/test/Analysis/CostModel/X86/interleaved-load-f64-stride-4.ll
@@ -27,7 +27,7 @@
 ; AVX2: LV: Found an estimated cost of 8 for VF 2 For instruction:   %v0 = load double, double* %in0, align 8
 ; AVX2: LV: Found an estimated cost of 12 for VF 4 For instruction:   %v0 = load double, double* %in0, align 8
 ; AVX2: LV: Found an estimated cost of 28 for VF 8 For instruction:   %v0 = load double, double* %in0, align 8
-; AVX2: LV: Found an estimated cost of 128 for VF 16 For instruction:   %v0 = load double, double* %in0, align 8
+; AVX2: LV: Found an estimated cost of 56 for VF 16 For instruction:   %v0 = load double, double* %in0, align 8
 ;
 ; AVX512: LV: Found an estimated cost of 1 for VF 1 For instruction:   %v0 = load double, double* %in0, align 8
 ; AVX512: LV: Found an estimated cost of 5 for VF 2 For instruction:   %v0 = load double, double* %in0, align 8
diff --git a/llvm/test/Analysis/CostModel/X86/interleaved-load-i64-stride-4.ll b/llvm/test/Analysis/CostModel/X86/interleaved-load-i64-stride-4.ll
--- a/llvm/test/Analysis/CostModel/X86/interleaved-load-i64-stride-4.ll
+++ b/llvm/test/Analysis/CostModel/X86/interleaved-load-i64-stride-4.ll
@@ -27,7 +27,7 @@
 ; AVX2: LV: Found an estimated cost of 8 for VF 2 For instruction:   %v0 = load i64, i64* %in0, align 8
 ; AVX2: LV: Found an estimated cost of 12 for VF 4 For instruction:   %v0 = load i64, i64* %in0, align 8
 ; AVX2: LV: Found an estimated cost of 28 for VF 8 For instruction:   %v0 = load i64, i64* %in0, align 8
-; AVX2: LV: Found an estimated cost of 208 for VF 16 For instruction:   %v0 = load i64, i64* %in0, align 8
+; AVX2: LV: Found an estimated cost of 56 for VF 16 For instruction:   %v0 = load i64, i64* %in0, align 8
 ;
 ; AVX512: LV: Found an estimated cost of 1 for VF 1 For instruction:   %v0 = load i64, i64* %in0, align 8
 ; AVX512: LV: Found an estimated cost of 5 for VF 2 For instruction:   %v0 = load i64, i64* %in0, align 8
diff --git a/llvm/test/Analysis/CostModel/X86/interleaved-store-f64-stride-4.ll b/llvm/test/Analysis/CostModel/X86/interleaved-store-f64-stride-4.ll
--- a/llvm/test/Analysis/CostModel/X86/interleaved-store-f64-stride-4.ll
+++ b/llvm/test/Analysis/CostModel/X86/interleaved-store-f64-stride-4.ll
@@ -27,7 +27,7 @@
 ; AVX2: LV: Found an estimated cost of 8 for VF 2 For instruction:   store double %v3, double* %out3, align 8
 ; AVX2: LV: Found an estimated cost of 12 for VF 4 For instruction:   store double %v3, double* %out3, align 8
 ; AVX2: LV: Found an estimated cost of 28 for VF 8 For instruction:   store double %v3, double* %out3, align 8
-; AVX2: LV: Found an estimated cost of 128 for VF 16 For instruction:   store double %v3, double* %out3, align 8
+; AVX2: LV: Found an estimated cost of 56 for VF 16 For instruction:   store double %v3, double* %out3, align 8
 ;
 ; AVX512: LV: Found an estimated cost of 1 for VF 1 For instruction:   store double %v3, double* %out3, align 8
 ; AVX512: LV: Found an estimated cost of 5 for VF 2 For instruction:   store double %v3, double* %out3, align 8
diff --git a/llvm/test/Analysis/CostModel/X86/interleaved-store-i64-stride-4.ll b/llvm/test/Analysis/CostModel/X86/interleaved-store-i64-stride-4.ll
--- a/llvm/test/Analysis/CostModel/X86/interleaved-store-i64-stride-4.ll
+++ b/llvm/test/Analysis/CostModel/X86/interleaved-store-i64-stride-4.ll
@@ -27,7 +27,7 @@
 ; AVX2: LV: Found an estimated cost of 8 for VF 2 For instruction:   store i64 %v3, i64* %out3, align 8
 ; AVX2: LV: Found an estimated cost of 12 for VF 4 For instruction:   store i64 %v3, i64* %out3, align 8
 ; AVX2: LV: Found an estimated cost of 28 for VF 8 For instruction:   store i64 %v3, i64* %out3, align 8
-; AVX2: LV: Found an estimated cost of 208 for VF 16 For instruction:   store i64 %v3, i64* %out3, align 8
+; AVX2: LV: Found an estimated cost of 56 for VF 16 For instruction:   store i64 %v3, i64* %out3, align 8
 ;
 ; AVX512: LV: Found an estimated cost of 1 for VF 1 For instruction:   store i64 %v3, i64* %out3, align 8
 ; AVX512: LV: Found an estimated cost of 5 for VF 2 For instruction:   store i64 %v3, i64* %out3, align 8