diff --git a/llvm/lib/CodeGen/MIRParser/MIParser.cpp b/llvm/lib/CodeGen/MIRParser/MIParser.cpp
--- a/llvm/lib/CodeGen/MIRParser/MIParser.cpp
+++ b/llvm/lib/CodeGen/MIRParser/MIParser.cpp
@@ -1011,10 +1011,6 @@
     Optional<unsigned> TiedDefIdx;
     if (parseMachineOperandAndTargetFlags(OpCode, Operands.size(), MO, TiedDefIdx))
       return true;
-    if ((OpCode == TargetOpcode::DBG_VALUE ||
-         OpCode == TargetOpcode::DBG_VALUE_LIST) &&
-        MO.isReg())
-      MO.setIsDebug();
     Operands.push_back(
         ParsedMachineOperand(MO, Loc, Token.location(), TiedDefIdx));
     if (Token.isNewlineOrEOF() || Token.is(MIToken::coloncolon) ||
diff --git a/llvm/lib/CodeGen/MachineInstr.cpp b/llvm/lib/CodeGen/MachineInstr.cpp
--- a/llvm/lib/CodeGen/MachineInstr.cpp
+++ b/llvm/lib/CodeGen/MachineInstr.cpp
@@ -294,6 +294,9 @@
       if (MCID->getOperandConstraint(OpNo, MCOI::EARLY_CLOBBER) != -1)
         NewMO->setIsEarlyClobber(true);
     }
+    // Ensure DBG_VALUE* sets RegState::Debug on all register use operands.
+    if (NewMO->isUse() && isDebugValue())
+      NewMO->setIsDebug();
   }
 }