diff --git a/openmp/libomptarget/DeviceRTL/include/Debug.h b/openmp/libomptarget/DeviceRTL/include/Debug.h
--- a/openmp/libomptarget/DeviceRTL/include/Debug.h
+++ b/openmp/libomptarget/DeviceRTL/include/Debug.h
@@ -25,9 +25,24 @@
 
 ///}
 
-// TODO: We need to allow actual printf.
-#define PRINTF(fmt, ...) (void)fmt;
+/// Print
+/// TODO: For now we have to use macros to guard the code because Clang lowers
+/// `printf` to different function calls on NVPTX and AMDGCN platforms, and it
+/// doesn't work for AMDGCN. After it can work on AMDGCN, we will remove the
+/// macro.
+/// {
+
+#ifndef __AMDGCN__
+extern "C" {
+int printf(const char *format, ...);
+}
+
+#define PRINTF(fmt, ...) (void)printf(fmt, __VA_ARGS__);
 #define PRINT(str) PRINTF("%s", str)
+#else
+#define PRINTF(fmt, ...)
+#define PRINT(str)
+#endif
 
 ///}