Index: llvm/lib/Transforms/InstCombine/InstCombineCompares.cpp
===================================================================
--- llvm/lib/Transforms/InstCombine/InstCombineCompares.cpp
+++ llvm/lib/Transforms/InstCombine/InstCombineCompares.cpp
@@ -1412,6 +1412,47 @@
   return nullptr;
 }
 
+/// Fold icmp involving trivial vscale calculations, e.g.:
+///   icmp Pred vscale, C
+///   icmp Pred (mul vscale, X), C
+///   icmp Pred (shl vscale, X), C
+/// We can use the maximum value of vscale if it exists in order to determine
+/// the result of certain cases at compile time.
+Instruction *InstCombinerImpl::foldICmpWithConstantVScale(ICmpInst &Cmp) {
+  CmpInst::Predicate Pred = Cmp.getPredicate();
+  Value *Op0 = Cmp.getOperand(0), *Op1 = Cmp.getOperand(1);
+
+  ConstantInt *CI = dyn_cast<ConstantInt>(Op1);
+  if (!CI)
+    return nullptr;
+
+  ConstantInt *VScaleMul = nullptr;
+  if (Pred == ICmpInst::ICMP_UGT &&
+      (match(Op0, m_VScale(DL)) ||
+       match(Op0, m_Mul(m_VScale(DL), m_ConstantInt(VScaleMul))))) {
+    // If we don't know the max value of vscale we can't fold anything.
+    if (!Cmp.getFunction()->hasFnAttribute(Attribute::VScaleRange))
+      return nullptr;
+
+    uint64_t MaxVScale = Cmp.getFunction()
+                             ->getFnAttribute(Attribute::VScaleRange)
+                             .getVScaleRangeArgs()
+                             .second;
+    if (MaxVScale == 0)
+      return nullptr;
+
+    // We know the maximum value of vscale * multipler and so we may
+    // be able to completely eliminate the icmp.
+    uint64_t MulVal = VScaleMul ? VScaleMul->getZExtValue() : 1;
+    uint64_t MaxLHSVal = MaxVScale * MulVal;
+
+    if (MaxLHSVal <= CI->getZExtValue())
+      return replaceInstUsesWith(Cmp, ConstantInt::get(Cmp.getType(), 0));
+  }
+
+  return nullptr;
+}
+
 /// Fold icmp Pred X, C.
 /// TODO: This code structure does not make sense. The saturating add fold
 /// should be moved to some other helper and extended as noted below (it is also
@@ -5841,6 +5882,9 @@
   if (Instruction *Res = foldICmpWithConstant(I))
     return Res;
 
+  if (Instruction *Res = foldICmpWithConstantVScale(I))
+    return Res;
+
   if (Instruction *Res = foldICmpWithDominatingICmp(I))
     return Res;
 
Index: llvm/lib/Transforms/InstCombine/InstCombineInternal.h
===================================================================
--- llvm/lib/Transforms/InstCombine/InstCombineInternal.h
+++ llvm/lib/Transforms/InstCombine/InstCombineInternal.h
@@ -649,6 +649,7 @@
   Instruction *foldICmpUsingKnownBits(ICmpInst &Cmp);
   Instruction *foldICmpWithDominatingICmp(ICmpInst &Cmp);
   Instruction *foldICmpWithConstant(ICmpInst &Cmp);
+  Instruction *foldICmpWithConstantVScale(ICmpInst &Cmp);
   Instruction *foldICmpInstWithConstant(ICmpInst &Cmp);
   Instruction *foldICmpInstWithConstantNotInt(ICmpInst &Cmp);
   Instruction *foldICmpBinOp(ICmpInst &Cmp, const SimplifyQuery &SQ);
Index: llvm/test/Transforms/InstCombine/icmp-vscale.ll
===================================================================
--- llvm/test/Transforms/InstCombine/icmp-vscale.ll
+++ llvm/test/Transforms/InstCombine/icmp-vscale.ll
@@ -37,6 +37,18 @@
   ret i1 %res
 }
 
+define i1 @uge_vscale8_x_4() vscale_range(0,16) {
+; CHECK-LABEL: @uge_vscale8_x_4(
+; CHECK-NEXT:  entry:
+; CHECK-NEXT:    ret i1 false
+;
+entry:
+  %vscale = call i8 @llvm.vscale.i8()
+  %num_els = mul i8 %vscale, 5
+  %res = icmp uge i8 %num_els, 128
+  ret i1 %res
+}
+
 define i1 @ult_vscale16() vscale_range(0,16) {
 ; CHECK-LABEL: @ult_vscale16(
 ; CHECK-NEXT:  entry:
@@ -82,6 +94,52 @@
   ret i1 %res
 }
 
+; Negative tests
+
+define i1 @fail_uge_vscale64_x_32_max32() vscale_range(0,32) {
+; CHECK-LABEL: @fail_uge_vscale64_x_32_max32(
+; CHECK-NEXT:  entry:
+; CHECK-NEXT:    [[VSCALE:%.*]] = call i64 @llvm.vscale.i64()
+; CHECK-NEXT:    [[RES:%.*]] = icmp ugt i64 [[VSCALE]], 31
+; CHECK-NEXT:    ret i1 [[RES]]
+;
+entry:
+  %vscale = call i64 @llvm.vscale.i64()
+  %num_els = shl i64 %vscale, 5
+  %res = icmp uge i64 %num_els, 1024
+  ret i1 %res
+}
+
+define i1 @fail_uge_vscale64_x_32_max0() vscale_range(0,0) {
+; CHECK-LABEL: @fail_uge_vscale64_x_32_max0(
+; CHECK-NEXT:  entry:
+; CHECK-NEXT:    [[VSCALE:%.*]] = call i64 @llvm.vscale.i64()
+; CHECK-NEXT:    [[NUM_ELS:%.*]] = mul i64 [[VSCALE]], 31
+; CHECK-NEXT:    [[RES:%.*]] = icmp ugt i64 [[NUM_ELS]], 12345677
+; CHECK-NEXT:    ret i1 [[RES]]
+;
+entry:
+  %vscale = call i64 @llvm.vscale.i64()
+  %num_els = mul i64 %vscale, 31
+  %res = icmp uge i64 %num_els, 12345678
+  ret i1 %res
+}
+
+define i1 @fail_uge_vscale64_x_val(i64 %val) vscale_range(0,32) {
+; CHECK-LABEL: @fail_uge_vscale64_x_val(
+; CHECK-NEXT:  entry:
+; CHECK-NEXT:    [[VSCALE:%.*]] = call i64 @llvm.vscale.i64()
+; CHECK-NEXT:    [[NUM_ELS:%.*]] = mul i64 [[VSCALE]], [[VAL:%.*]]
+; CHECK-NEXT:    [[RES:%.*]] = icmp ugt i64 [[NUM_ELS]], 1023
+; CHECK-NEXT:    ret i1 [[RES]]
+;
+entry:
+  %vscale = call i64 @llvm.vscale.i64()
+  %num_els = mul i64 %vscale, %val
+  %res = icmp uge i64 %num_els, 1024
+  ret i1 %res
+}
+
 declare i8 @llvm.vscale.i8()
 declare i16 @llvm.vscale.i16()
 declare i32 @llvm.vscale.i32()