diff --git a/clang/include/clang/Basic/Attr.td b/clang/include/clang/Basic/Attr.td
--- a/clang/include/clang/Basic/Attr.td
+++ b/clang/include/clang/Basic/Attr.td
@@ -2940,6 +2940,13 @@
   let ASTNode = 0;
 }
 
+def DisableSanitizerInstrumentation : InheritableAttr {
+  let Spellings = [Clang<"disable_sanitizer_instrumentation">];
+  let Subjects = SubjectList<[Function]>;
+  let Documentation = [DisableSanitizerInstrumentationDocs];
+  let SimpleHandler = 1;
+}
+
 def CFICanonicalJumpTable : InheritableAttr {
   let Spellings = [Clang<"cfi_canonical_jump_table">];
   let Subjects = SubjectList<[Function], ErrorDiag>;
diff --git a/clang/include/clang/Basic/AttrDocs.td b/clang/include/clang/Basic/AttrDocs.td
--- a/clang/include/clang/Basic/AttrDocs.td
+++ b/clang/include/clang/Basic/AttrDocs.td
@@ -2592,6 +2592,17 @@
   }];
 }
 
+def DisableSanitizerInstrumentationDocs : Documentation {
+  let Category = DocCatFunction;
+  let Content = [{
+Use the ``disable_sanitizer_instrumentation`` attribute on a function to
+specify that no sanitizer instrumentation should be applied.
+
+This is not the same as ``__attribute__((no_sanitize(...)))``, which depending
+on the tool may still insert instrumentation to prevent false positive reports.
+  }];
+}
+
 def NoSanitizeAddressDocs : Documentation {
   let Category = DocCatFunction;
   // This function has multiple distinct spellings, and so it requires a custom
diff --git a/clang/lib/CodeGen/CodeGenFunction.h b/clang/lib/CodeGen/CodeGenFunction.h
--- a/clang/lib/CodeGen/CodeGenFunction.h
+++ b/clang/lib/CodeGen/CodeGenFunction.h
@@ -2286,6 +2286,10 @@
   /// instrumented with __cyg_profile_func_* calls
   bool ShouldInstrumentFunction();
 
+  /// ShouldSkipSanitizerInstrumentation - Return true if the current function
+  /// should not be instrumented with sanitizers.
+  bool ShouldSkipSanitizerInstrumentation();
+
   /// ShouldXRayInstrument - Return true if the current function should be
   /// instrumented with XRay nop sleds.
   bool ShouldXRayInstrumentFunction() const;
diff --git a/clang/lib/CodeGen/CodeGenFunction.cpp b/clang/lib/CodeGen/CodeGenFunction.cpp
--- a/clang/lib/CodeGen/CodeGenFunction.cpp
+++ b/clang/lib/CodeGen/CodeGenFunction.cpp
@@ -381,6 +381,9 @@
                        "__cyg_profile_func_exit");
   }
 
+  if (ShouldSkipSanitizerInstrumentation())
+    CurFn->addFnAttr(llvm::Attribute::DisableSanitizerInstrumentation);
+
   // Emit debug descriptor for function end.
   if (CGDebugInfo *DI = getDebugInfo())
     DI->EmitFunctionEnd(Builder, CurFn);
@@ -517,6 +520,14 @@
   return true;
 }
 
+bool CodeGenFunction::ShouldSkipSanitizerInstrumentation() {
+  if (!CurFuncDecl)
+    return false;
+  if (CurFuncDecl->hasAttr<DisableSanitizerInstrumentationAttr>())
+    return true;
+  return false;
+}
+
 /// ShouldXRayInstrument - Return true if the current function should be
 /// instrumented with XRay nop sleds.
 bool CodeGenFunction::ShouldXRayInstrumentFunction() const {
diff --git a/clang/test/CodeGen/attr-no-sanitize-coverage.c b/clang/test/CodeGen/attr-no-sanitize-coverage.c
new file mode 100644
--- /dev/null
+++ b/clang/test/CodeGen/attr-no-sanitize-coverage.c
@@ -0,0 +1,11 @@
+// RUN: %clang_cc1 -debug-info-kind=limited %s -emit-llvm -o - | FileCheck %s
+
+void t1() __attribute__((disable_sanitizer_instrumentation)) {
+}
+// CHECK: disable_sanitizer_instrumentation
+// CHECK-NEXT: void @t1
+
+// CHECK-NOT: disable_sanitizer_instrumentation
+// CHECK: void @t2
+void t2() {
+}
diff --git a/clang/test/Misc/pragma-attribute-supported-attributes-list.test b/clang/test/Misc/pragma-attribute-supported-attributes-list.test
--- a/clang/test/Misc/pragma-attribute-supported-attributes-list.test
+++ b/clang/test/Misc/pragma-attribute-supported-attributes-list.test
@@ -56,6 +56,7 @@
 // CHECK-NEXT: DLLExport (SubjectMatchRule_function, SubjectMatchRule_variable, SubjectMatchRule_record, SubjectMatchRule_objc_interface)
 // CHECK-NEXT: DLLImport (SubjectMatchRule_function, SubjectMatchRule_variable, SubjectMatchRule_record, SubjectMatchRule_objc_interface)
 // CHECK-NEXT: Destructor (SubjectMatchRule_function)
+// CHECK-NEXT: DisableSanitizerInstrumentation (SubjectMatchRule_function)
 // CHECK-NEXT: DisableTailCalls (SubjectMatchRule_function, SubjectMatchRule_objc_method)
 // CHECK-NEXT: EnableIf (SubjectMatchRule_function)
 // CHECK-NEXT: EnforceTCB (SubjectMatchRule_function)
diff --git a/llvm/include/llvm/AsmParser/LLToken.h b/llvm/include/llvm/AsmParser/LLToken.h
--- a/llvm/include/llvm/AsmParser/LLToken.h
+++ b/llvm/include/llvm/AsmParser/LLToken.h
@@ -190,6 +190,7 @@
   kw_convergent,
   kw_dereferenceable,
   kw_dereferenceable_or_null,
+  kw_disable_sanitizer_instrumentation,
   kw_elementtype,
   kw_inaccessiblememonly,
   kw_inaccessiblemem_or_argmemonly,
diff --git a/llvm/include/llvm/Bitcode/LLVMBitCodes.h b/llvm/include/llvm/Bitcode/LLVMBitCodes.h
--- a/llvm/include/llvm/Bitcode/LLVMBitCodes.h
+++ b/llvm/include/llvm/Bitcode/LLVMBitCodes.h
@@ -671,6 +671,7 @@
   ATTR_KIND_SWIFT_ASYNC = 75,
   ATTR_KIND_NO_SANITIZE_COVERAGE = 76,
   ATTR_KIND_ELEMENTTYPE = 77,
+  ATTR_DISABLE_SANITIZER_INSTRUMENTATION = 78,
 };
 
 enum ComdatSelectionKindCodes {
diff --git a/llvm/include/llvm/IR/Attributes.td b/llvm/include/llvm/IR/Attributes.td
--- a/llvm/include/llvm/IR/Attributes.td
+++ b/llvm/include/llvm/IR/Attributes.td
@@ -86,6 +86,9 @@
 def DereferenceableOrNull : IntAttr<"dereferenceable_or_null",
                                     [ParamAttr, RetAttr]>;
 
+/// Do not instrument function with sanitizers.
+def DisableSanitizerInstrumentation: EnumAttr<"disable_sanitizer_instrumentation", [FnAttr]>;
+
 /// Provide pointer element type to intrinsic.
 def ElementType : TypeAttr<"elementtype", [ParamAttr]>;
 
diff --git a/llvm/lib/Bitcode/Writer/BitcodeWriter.cpp b/llvm/lib/Bitcode/Writer/BitcodeWriter.cpp
--- a/llvm/lib/Bitcode/Writer/BitcodeWriter.cpp
+++ b/llvm/lib/Bitcode/Writer/BitcodeWriter.cpp
@@ -628,6 +628,8 @@
     return bitc::ATTR_KIND_IN_ALLOCA;
   case Attribute::Cold:
     return bitc::ATTR_KIND_COLD;
+  case Attribute::DisableSanitizerInstrumentation:
+    return bitc::ATTR_DISABLE_SANITIZER_INSTRUMENTATION;
   case Attribute::Hot:
     return bitc::ATTR_KIND_HOT;
   case Attribute::ElementType:
diff --git a/llvm/lib/Transforms/Utils/CodeExtractor.cpp b/llvm/lib/Transforms/Utils/CodeExtractor.cpp
--- a/llvm/lib/Transforms/Utils/CodeExtractor.cpp
+++ b/llvm/lib/Transforms/Utils/CodeExtractor.cpp
@@ -943,6 +943,7 @@
       // Those attributes should be safe to propagate to the extracted function.
       case Attribute::AlwaysInline:
       case Attribute::Cold:
+      case Attribute::DisableSanitizerInstrumentation:
       case Attribute::Hot:
       case Attribute::NoRecurse:
       case Attribute::InlineHint: