diff --git a/openmp/libomptarget/deviceRTLs/nvptx/CMakeLists.txt b/openmp/libomptarget/deviceRTLs/nvptx/CMakeLists.txt
--- a/openmp/libomptarget/deviceRTLs/nvptx/CMakeLists.txt
+++ b/openmp/libomptarget/deviceRTLs/nvptx/CMakeLists.txt
@@ -159,6 +159,7 @@
              -Xclang -aux-triple -Xclang ${aux_triple}
              -fopenmp -fopenmp-cuda-mode -Xclang -fopenmp-is-device
              -Xclang -target-feature -Xclang +ptx61
+             -mllvm -openmp-opt-disable
              -D__CUDACC__
              -I${devicertl_base_directory}
              -I${devicertl_common_directory}/include