diff --git a/compiler-rt/lib/scudo/standalone/memtag.h b/compiler-rt/lib/scudo/standalone/memtag.h
--- a/compiler-rt/lib/scudo/standalone/memtag.h
+++ b/compiler-rt/lib/scudo/standalone/memtag.h
@@ -319,7 +319,8 @@
 
 template <typename Config>
 inline constexpr bool allocatorSupportsMemoryTagging() {
-  return archSupportsMemoryTagging() && Config::MaySupportMemoryTagging;
+  return archSupportsMemoryTagging() && Config::MaySupportMemoryTagging &&
+         (1 << SCUDO_MIN_ALIGNMENT_LOG) >= archMemoryTagGranuleSize();
 }
 
 } // namespace scudo