diff --git a/clang/include/clang/StaticAnalyzer/Core/BugReporter/BugReporter.h b/clang/include/clang/StaticAnalyzer/Core/BugReporter/BugReporter.h
--- a/clang/include/clang/StaticAnalyzer/Core/BugReporter/BugReporter.h
+++ b/clang/include/clang/StaticAnalyzer/Core/BugReporter/BugReporter.h
@@ -432,6 +432,8 @@
   void markInteresting(SymbolRef sym, bugreporter::TrackingKind TKind =
                                           bugreporter::TrackingKind::Thorough);
 
+  void markNotInteresting(SymbolRef sym);
+
   /// Marks a region as interesting. Different kinds of interestingness will
   /// be processed differently by visitors (e.g. if the tracking kind is
   /// condition, will append "will be used as a condition" to the message).
@@ -439,6 +441,8 @@
       const MemRegion *R,
       bugreporter::TrackingKind TKind = bugreporter::TrackingKind::Thorough);
 
+  void markNotInteresting(const MemRegion *R);
+
   /// Marks a symbolic value as interesting. Different kinds of interestingness
   /// will be processed differently by visitors (e.g. if the tracking kind is
   /// condition, will append "will be used as a condition" to the message).
diff --git a/clang/lib/StaticAnalyzer/Core/BugReporter.cpp b/clang/lib/StaticAnalyzer/Core/BugReporter.cpp
--- a/clang/lib/StaticAnalyzer/Core/BugReporter.cpp
+++ b/clang/lib/StaticAnalyzer/Core/BugReporter.cpp
@@ -2253,6 +2253,14 @@
     markInteresting(meta->getRegion(), TKind);
 }
 
+void PathSensitiveBugReport::markNotInteresting(SymbolRef sym) {
+  if (!sym)
+    return;
+  InterestingSymbols.erase(sym);
+  if (const auto *meta = dyn_cast<SymbolMetadata>(sym))
+    markNotInteresting(meta->getRegion());
+}
+
 void PathSensitiveBugReport::markInteresting(const MemRegion *R,
                                              bugreporter::TrackingKind TKind) {
   if (!R)
@@ -2265,6 +2273,17 @@
     markInteresting(SR->getSymbol(), TKind);
 }
 
+void PathSensitiveBugReport::markNotInteresting(const MemRegion *R) {
+  if (!R)
+    return;
+
+  R = R->getBaseRegion();
+  InterestingRegions.erase(R);
+
+  if (const auto *SR = dyn_cast<SymbolicRegion>(R))
+    markNotInteresting(SR->getSymbol());
+}
+
 void PathSensitiveBugReport::markInteresting(SVal V,
                                              bugreporter::TrackingKind TKind) {
   markInteresting(V.getAsRegion(), TKind);