diff --git a/llvm/lib/Transforms/IPO/OpenMPOpt.cpp b/llvm/lib/Transforms/IPO/OpenMPOpt.cpp
--- a/llvm/lib/Transforms/IPO/OpenMPOpt.cpp
+++ b/llvm/lib/Transforms/IPO/OpenMPOpt.cpp
@@ -486,7 +486,8 @@
   BooleanStateWithPtrSetVector<CallBase> ReachedUnknownParallelRegions;
 
   /// State to track if we are in SPMD-mode, assumed or know, and why we decided
-  /// we cannot be.
+  /// we cannot be. If it is assumed, then RequiresFullRuntime should also be
+  /// false.
   BooleanStateWithPtrSetVector<Instruction> SPMDCompatibilityTracker;
 
   /// The __kmpc_target_init call in this kernel, if any. If we find more than
@@ -2803,9 +2804,32 @@
       return Val;
     };
 
+    Attributor::SimplifictionCallbackTy IsGenericModeSimplifyCB =
+        [&](const IRPosition &IRP, const AbstractAttribute *AA,
+            bool &UsedAssumedInformation) -> Optional<Value *> {
+      // IRP represents the "RequiresFullRuntime" argument of an
+      // __kmpc_target_init or __kmpc_target_deinit call. We will answer this
+      // one with the internal state of the SPMDCompatibilityTracker, so if
+      // generic then true, if SPMD then false.
+      if (!isValidState())
+        return nullptr;
+      if (!SPMDCompatibilityTracker.isAtFixpoint()) {
+        if (AA)
+          A.recordDependence(*this, *AA, DepClassTy::OPTIONAL);
+        UsedAssumedInformation = true;
+      } else {
+        UsedAssumedInformation = false;
+      }
+      auto *Val = ConstantInt::getBool(IRP.getAnchorValue().getContext(),
+                                       !SPMDCompatibilityTracker.isAssumed());
+      return Val;
+    };
+
     constexpr const int InitIsSPMDArgNo = 1;
     constexpr const int DeinitIsSPMDArgNo = 1;
     constexpr const int InitUseStateMachineArgNo = 2;
+    constexpr const int InitRequiresFullRuntimeArgNo = 3;
+    constexpr const int DeinitRequiresFullRuntimeArgNo = 2;
     A.registerSimplificationCallback(
         IRPosition::callsite_argument(*KernelInitCB, InitUseStateMachineArgNo),
         StateMachineSimplifyCB);
@@ -2815,6 +2839,14 @@
     A.registerSimplificationCallback(
         IRPosition::callsite_argument(*KernelDeinitCB, DeinitIsSPMDArgNo),
         IsSPMDModeSimplifyCB);
+    A.registerSimplificationCallback(
+        IRPosition::callsite_argument(*KernelInitCB,
+                                      InitRequiresFullRuntimeArgNo),
+        IsGenericModeSimplifyCB);
+    A.registerSimplificationCallback(
+        IRPosition::callsite_argument(*KernelDeinitCB,
+                                      DeinitRequiresFullRuntimeArgNo),
+        IsGenericModeSimplifyCB);
 
     // Check if we know we are in SPMD-mode already.
     ConstantInt *IsSPMDArg =
@@ -2883,6 +2915,8 @@
     const int InitIsSPMDArgNo = 1;
     const int DeinitIsSPMDArgNo = 1;
     const int InitUseStateMachineArgNo = 2;
+    const int InitRequiresFullRuntimeArgNo = 3;
+    const int DeinitRequiresFullRuntimeArgNo = 2;
 
     auto &Ctx = getAnchorValue().getContext();
     A.changeUseAfterManifest(KernelInitCB->getArgOperandUse(InitIsSPMDArgNo),
@@ -2893,6 +2927,13 @@
     A.changeUseAfterManifest(
         KernelDeinitCB->getArgOperandUse(DeinitIsSPMDArgNo),
         *ConstantInt::getBool(Ctx, 1));
+    A.changeUseAfterManifest(
+        KernelInitCB->getArgOperandUse(InitRequiresFullRuntimeArgNo),
+        *ConstantInt::getBool(Ctx, 0));
+    A.changeUseAfterManifest(
+        KernelDeinitCB->getArgOperandUse(DeinitRequiresFullRuntimeArgNo),
+        *ConstantInt::getBool(Ctx, 0));
+
     ++NumOpenMPTargetRegionKernelsSPMD;
 
     auto Remark = [&](OptimizationRemark OR) {