diff --git a/llvm/include/llvm/MC/MCAsmInfo.h b/llvm/include/llvm/MC/MCAsmInfo.h
--- a/llvm/include/llvm/MC/MCAsmInfo.h
+++ b/llvm/include/llvm/MC/MCAsmInfo.h
@@ -153,6 +153,9 @@
   /// This is appended to emitted labels.  Defaults to ":"
   const char *LabelSuffix;
 
+  /// Emit labels in purely upper case. Defaults to false.
+  bool EmitLabelsInUpperCase = false;
+
   // Print the EH begin symbol with an assignment. Defaults to false.
   bool UseAssignmentForEHBegin = false;
 
@@ -637,6 +640,7 @@
     return EmitGNUAsmStartIndentationMarker;
   }
   const char *getLabelSuffix() const { return LabelSuffix; }
+  bool shouldEmitLabelsInUpperCase() const { return EmitLabelsInUpperCase; }
 
   bool useAssignmentForEHBegin() const { return UseAssignmentForEHBegin; }
   bool needsLocalForSize() const { return NeedsLocalForSize; }
diff --git a/llvm/lib/MC/MCParser/AsmParser.cpp b/llvm/lib/MC/MCParser/AsmParser.cpp
--- a/llvm/lib/MC/MCParser/AsmParser.cpp
+++ b/llvm/lib/MC/MCParser/AsmParser.cpp
@@ -1231,7 +1231,8 @@
 
     MCSymbol *Sym = getContext().getInlineAsmLabel(SymbolName);
     if (!Sym)
-      Sym = getContext().getOrCreateSymbol(SymbolName);
+      Sym = getContext().getOrCreateSymbol(
+          MAI.shouldEmitLabelsInUpperCase() ? SymbolName.upper() : SymbolName);
 
     // If this is an absolute variable reference, substitute it now to preserve
     // semantics in the face of reassignment.
@@ -6212,8 +6213,10 @@
     return Error(LabelLoc,
                  "Cannot have just a label for an HLASM inline asm statement");
 
-  // FIXME: Later on, ensure emitted labels are case-insensitive.
-  MCSymbol *Sym = getContext().getOrCreateSymbol(LabelVal);
+  MCSymbol *Sym = getContext().getOrCreateSymbol(
+      getContext().getAsmInfo()->shouldEmitLabelsInUpperCase()
+          ? LabelVal.upper()
+          : LabelVal);
 
   getTargetParser().doBeforeLabelEmit(Sym);
 
diff --git a/llvm/lib/Target/SystemZ/MCTargetDesc/SystemZMCAsmInfo.cpp b/llvm/lib/Target/SystemZ/MCTargetDesc/SystemZMCAsmInfo.cpp
--- a/llvm/lib/Target/SystemZ/MCTargetDesc/SystemZMCAsmInfo.cpp
+++ b/llvm/lib/Target/SystemZ/MCTargetDesc/SystemZMCAsmInfo.cpp
@@ -31,6 +31,7 @@
   StarIsPC = (AssemblerDialect == AD_HLASM);
   EmitGNUAsmStartIndentationMarker = (AssemblerDialect == AD_ATT);
   AllowAtInName = (AssemblerDialect == AD_HLASM);
+  EmitLabelsInUpperCase = (AssemblerDialect == AD_HLASM);
 
   ZeroDirective = "\t.space\t";
   Data64bitsDirective = "\t.quad\t";
diff --git a/llvm/unittests/MC/SystemZ/SystemZAsmLexerTest.cpp b/llvm/unittests/MC/SystemZ/SystemZAsmLexerTest.cpp
--- a/llvm/unittests/MC/SystemZ/SystemZAsmLexerTest.cpp
+++ b/llvm/unittests/MC/SystemZ/SystemZAsmLexerTest.cpp
@@ -49,6 +49,7 @@
   }
   void setAllowDotIsPC(bool Value) { DotIsPC = Value; }
   void setAssemblerDialect(unsigned Value) { AssemblerDialect = Value; }
+  void setEmitLabelsInUpperCase(bool Value) { EmitLabelsInUpperCase = Value; }
 };
 
 // Setup a testing class that the GTest framework can call.
@@ -750,4 +751,36 @@
   AsmStr += "#";
   EXPECT_EQ(true, MUPMAI->isValidUnquotedName(AsmStr));
 }
+
+TEST_F(SystemZAsmLexerTest, CheckLabelCaseUpperCase2) {
+  StringRef AsmStr = "label\nlabel";
+
+  // Setup.
+  setupCallToAsmParser(AsmStr);
+
+  // Lex initially to get the string.
+  Parser->getLexer().Lex();
+
+  const MCExpr *Expr;
+  bool ParsePrimaryExpr = Parser->parseExpression(Expr);
+  EXPECT_EQ(ParsePrimaryExpr, false);
+
+  const MCSymbolRefExpr *SymbolExpr = dyn_cast<MCSymbolRefExpr>(Expr);
+  EXPECT_NE(SymbolExpr, nullptr);
+  EXPECT_NE(&SymbolExpr->getSymbol(), nullptr);
+  EXPECT_EQ((&SymbolExpr->getSymbol())->getName(), StringRef("label"));
+
+  // Lex the end of statement token.
+  Parser->getLexer().Lex();
+
+  MUPMAI->setEmitLabelsInUpperCase(true);
+
+  ParsePrimaryExpr = Parser->parseExpression(Expr);
+  EXPECT_EQ(ParsePrimaryExpr, false);
+
+  SymbolExpr = dyn_cast<MCSymbolRefExpr>(Expr);
+  EXPECT_NE(SymbolExpr, nullptr);
+  EXPECT_NE(&SymbolExpr->getSymbol(), nullptr);
+  EXPECT_EQ((&SymbolExpr->getSymbol())->getName(), StringRef("LABEL"));
+}
 } // end anonymous namespace