diff --git a/llvm/lib/Transforms/Scalar/LoopStrengthReduce.cpp b/llvm/lib/Transforms/Scalar/LoopStrengthReduce.cpp
--- a/llvm/lib/Transforms/Scalar/LoopStrengthReduce.cpp
+++ b/llvm/lib/Transforms/Scalar/LoopStrengthReduce.cpp
@@ -2712,13 +2712,13 @@
       if (const SCEVConstant *Factor =
             dyn_cast_or_null<SCEVConstant>(getExactSDiv(NewStride, OldStride,
                                                         SE, true))) {
-        if (Factor->getAPInt().getMinSignedBits() <= 64)
+        if (Factor->getAPInt().getMinSignedBits() <= 64 && !Factor->isZero())
           Factors.insert(Factor->getAPInt().getSExtValue());
       } else if (const SCEVConstant *Factor =
                    dyn_cast_or_null<SCEVConstant>(getExactSDiv(OldStride,
                                                                NewStride,
                                                                SE, true))) {
-        if (Factor->getAPInt().getMinSignedBits() <= 64)
+        if (Factor->getAPInt().getMinSignedBits() <= 64 && !Factor->isZero())
           Factors.insert(Factor->getAPInt().getSExtValue());
       }
     }
diff --git a/llvm/test/Transforms/LoopStrengthReduce/pr50765.ll b/llvm/test/Transforms/LoopStrengthReduce/pr50765.ll
--- a/llvm/test/Transforms/LoopStrengthReduce/pr50765.ll
+++ b/llvm/test/Transforms/LoopStrengthReduce/pr50765.ll
@@ -1,6 +1,4 @@
 ; RUN: opt -S -loop-reduce < %s | FileCheck %s
-; XFAIL: *
-; REQUIRES: asserts
 ;
 ;This test produces zero factor that becomes a denumerator and fails an assetion.