diff --git a/llvm/lib/Analysis/ScalarEvolution.cpp b/llvm/lib/Analysis/ScalarEvolution.cpp
--- a/llvm/lib/Analysis/ScalarEvolution.cpp
+++ b/llvm/lib/Analysis/ScalarEvolution.cpp
@@ -1060,9 +1060,6 @@
   if (!Op->getType()->isPointerTy())
     return Op;
 
-  assert(!getDataLayout().isNonIntegralPointerType(Op->getType()) &&
-         "Source pointer type must be integral for ptrtoint!");
-
   // What would be an ID for such a SCEV cast expression?
   FoldingSetNodeID ID;
   ID.AddInteger(scPtrToInt);