diff --git a/clang/lib/StaticAnalyzer/Core/RangeConstraintManager.cpp b/clang/lib/StaticAnalyzer/Core/RangeConstraintManager.cpp
--- a/clang/lib/StaticAnalyzer/Core/RangeConstraintManager.cpp
+++ b/clang/lib/StaticAnalyzer/Core/RangeConstraintManager.cpp
@@ -1487,15 +1487,18 @@
       // This is an infeasible assumption.
       return nullptr;
 
-    ProgramStateRef NewState = setConstraint(State, Sym, NewConstraint);
-    if (auto Equality = EqualityInfo::extract(Sym, Int, Adjustment)) {
-      // If the original assumption is not Sym + Adjustment !=/</> Int,
-      // we should invert IsEquality flag.
-      Equality->IsEquality = Equality->IsEquality != EQ;
-      return track(NewState, *Equality);
+    if (ProgramStateRef NewState = setConstraint(State, Sym, NewConstraint)) {
+      if (auto Equality = EqualityInfo::extract(Sym, Int, Adjustment)) {
+        // If the original assumption is not Sym + Adjustment !=/</> Int,
+        // we should invert IsEquality flag.
+        Equality->IsEquality = Equality->IsEquality != EQ;
+        return track(NewState, *Equality);
+      }
+
+      return NewState;
     }
 
-    return NewState;
+    return nullptr;
   }
 
   ProgramStateRef track(ProgramStateRef State, EqualityInfo ToTrack) {
diff --git a/clang/test/Analysis/PR50268.c b/clang/test/Analysis/PR50268.c
new file mode 100644
--- /dev/null
+++ b/clang/test/Analysis/PR50268.c
@@ -0,0 +1,12 @@
+// RUN: %clang_analyze_cc1 -w -analyzer-checker=core -verify %s
+
+// expected-no-diagnostics
+
+unsigned long a, c;
+int b;
+void d() {
+  c -= a;
+  0 >= b;
+  c != b;
+  c ? 0 : 2; // expected no crash
+}