diff --git a/clang/include/clang/Basic/Attr.td b/clang/include/clang/Basic/Attr.td
--- a/clang/include/clang/Basic/Attr.td
+++ b/clang/include/clang/Basic/Attr.td
@@ -2812,7 +2812,7 @@
                    C2x<"", "nodiscard", 201904>,
                    CXX11<"clang", "warn_unused_result">,
                    GCC<"warn_unused_result">];
-  let Subjects = SubjectList<[ObjCMethod, Enum, Record, FunctionLike]>;
+  let Subjects = SubjectList<[ObjCMethod, Enum, Record, FunctionLike, TypedefName]>;
   let Args = [StringArgument<"Message", 1>];
   let Documentation = [WarnUnusedResultsDocs];
   let AdditionalMembers = [{
diff --git a/clang/lib/AST/Expr.cpp b/clang/lib/AST/Expr.cpp
--- a/clang/lib/AST/Expr.cpp
+++ b/clang/lib/AST/Expr.cpp
@@ -1413,6 +1413,10 @@
     if (const auto *A = TD->getAttr<WarnUnusedResultAttr>())
       return A;
 
+  if (const auto *TD = getCallReturnType(Ctx)->getAs<TypedefType>())
+    if (const auto *A = TD->getDecl()->getAttr<WarnUnusedResultAttr>())
+      return A;
+
   // Otherwise, see if the callee is marked nodiscard and return that attribute
   // instead.
   const Decl *D = getCalleeDecl();
diff --git a/clang/test/SemaCXX/warn-unused-result.cpp b/clang/test/SemaCXX/warn-unused-result.cpp
--- a/clang/test/SemaCXX/warn-unused-result.cpp
+++ b/clang/test/SemaCXX/warn-unused-result.cpp
@@ -254,3 +254,15 @@
 
 void i([[nodiscard]] bool (*fp)()); // expected-warning {{'nodiscard' attribute only applies to functions, classes, or enumerations}}
 }
+
+namespace unused_typedef_result {
+[[clang::warn_unused_result]] typedef void *p;
+p f1();
+void f2() {
+  f1(); // expected-warning {{ignoring return value}}
+  void *(*p1)();
+  p1(); // no warning
+  p (*p2)();
+  p2(); // expected-warning {{ignoring return value}}
+}
+}