diff --git a/libcxx/CMakeLists.txt b/libcxx/CMakeLists.txt
--- a/libcxx/CMakeLists.txt
+++ b/libcxx/CMakeLists.txt
@@ -425,9 +425,6 @@
 
 file(MAKE_DIRECTORY "${LIBCXX_BINARY_INCLUDE_DIR}")
 
-set(LIBCXX_INSTALL_PREFIX "" CACHE STRING "Define libc++ destination prefix.")
-set(LIBCXX_INSTALL_HEADER_PREFIX "" CACHE STRING "Define libc++ header destination prefix.")
-
 set(CMAKE_ARCHIVE_OUTPUT_DIRECTORY ${LIBCXX_LIBRARY_DIR})
 set(CMAKE_LIBRARY_OUTPUT_DIRECTORY ${LIBCXX_LIBRARY_DIR})
 set(CMAKE_RUNTIME_OUTPUT_DIRECTORY ${LIBCXX_LIBRARY_DIR})
diff --git a/libcxx/cmake/Modules/HandleLibCXXABI.cmake b/libcxx/cmake/Modules/HandleLibCXXABI.cmake
--- a/libcxx/cmake/Modules/HandleLibCXXABI.cmake
+++ b/libcxx/cmake/Modules/HandleLibCXXABI.cmake
@@ -63,7 +63,7 @@
 
         if (LIBCXX_INSTALL_HEADERS)
           install(FILES "${LIBCXX_BINARY_INCLUDE_DIR}/${fpath}"
-            DESTINATION ${LIBCXX_INSTALL_HEADER_PREFIX}include/c++/v1/${dstdir}
+            DESTINATION include/c++/v1/${dstdir}
             COMPONENT cxx-headers
             PERMISSIONS OWNER_READ OWNER_WRITE GROUP_READ WORLD_READ
             )
diff --git a/libcxx/docs/BuildingLibcxx.rst b/libcxx/docs/BuildingLibcxx.rst
--- a/libcxx/docs/BuildingLibcxx.rst
+++ b/libcxx/docs/BuildingLibcxx.rst
@@ -235,12 +235,6 @@
   Extra suffix to append to the directory where libraries are to be installed.
   This option overrides `LLVM_LIBDIR_SUFFIX`.
 
-.. option:: LIBCXX_INSTALL_PREFIX:STRING
-
-  **Default**: ``""``
-
-  Define libc++ destination prefix.
-
 .. option:: LIBCXX_HERMETIC_STATIC_LIBRARY:BOOL
 
   **Default**: ``OFF``
diff --git a/libcxx/include/CMakeLists.txt b/libcxx/include/CMakeLists.txt
--- a/libcxx/include/CMakeLists.txt
+++ b/libcxx/include/CMakeLists.txt
@@ -219,7 +219,7 @@
   foreach(file ${files})
     get_filename_component(dir ${file} DIRECTORY)
     install(FILES ${file}
-      DESTINATION ${LIBCXX_INSTALL_HEADER_PREFIX}include/c++/v1/${dir}
+      DESTINATION include/c++/v1/${dir}
       COMPONENT cxx-headers
       PERMISSIONS OWNER_READ OWNER_WRITE GROUP_READ WORLD_READ
     )
@@ -227,7 +227,7 @@
 
   # Install the generated __config_site.
   install(FILES ${LIBCXX_GENERATED_INCLUDE_DIR}/__config_site
-    DESTINATION ${LIBCXX_INSTALL_HEADER_PREFIX}include/c++/v1
+    DESTINATION include/c++/v1
     PERMISSIONS OWNER_READ OWNER_WRITE GROUP_READ WORLD_READ
     COMPONENT cxx-headers)
 
diff --git a/libcxx/src/CMakeLists.txt b/libcxx/src/CMakeLists.txt
--- a/libcxx/src/CMakeLists.txt
+++ b/libcxx/src/CMakeLists.txt
@@ -366,30 +366,30 @@
 
 if (LIBCXX_INSTALL_SHARED_LIBRARY)
   install(TARGETS cxx_shared
-    ARCHIVE DESTINATION ${LIBCXX_INSTALL_PREFIX}${LIBCXX_INSTALL_LIBRARY_DIR} COMPONENT cxx
-    LIBRARY DESTINATION ${LIBCXX_INSTALL_PREFIX}${LIBCXX_INSTALL_LIBRARY_DIR} COMPONENT cxx
-    RUNTIME DESTINATION ${LIBCXX_INSTALL_PREFIX}bin COMPONENT cxx)
+    ARCHIVE DESTINATION ${LIBCXX_INSTALL_LIBRARY_DIR} COMPONENT cxx
+    LIBRARY DESTINATION ${LIBCXX_INSTALL_LIBRARY_DIR} COMPONENT cxx
+    RUNTIME DESTINATION bin COMPONENT cxx)
 endif()
 
 if (LIBCXX_INSTALL_STATIC_LIBRARY)
   install(TARGETS cxx_static
-    ARCHIVE DESTINATION ${LIBCXX_INSTALL_PREFIX}${LIBCXX_INSTALL_LIBRARY_DIR} COMPONENT cxx
-    LIBRARY DESTINATION ${LIBCXX_INSTALL_PREFIX}${LIBCXX_INSTALL_LIBRARY_DIR} COMPONENT cxx
-    RUNTIME DESTINATION ${LIBCXX_INSTALL_PREFIX}bin COMPONENT cxx)
+    ARCHIVE DESTINATION ${LIBCXX_INSTALL_LIBRARY_DIR} COMPONENT cxx
+    LIBRARY DESTINATION ${LIBCXX_INSTALL_LIBRARY_DIR} COMPONENT cxx
+    RUNTIME DESTINATION bin COMPONENT cxx)
 endif()
 
 if(LIBCXX_INSTALL_EXPERIMENTAL_LIBRARY)
   install(TARGETS cxx_experimental
-    LIBRARY DESTINATION ${LIBCXX_INSTALL_PREFIX}${LIBCXX_INSTALL_LIBRARY_DIR} COMPONENT cxx
-    ARCHIVE DESTINATION ${LIBCXX_INSTALL_PREFIX}${LIBCXX_INSTALL_LIBRARY_DIR} COMPONENT cxx
-    RUNTIME DESTINATION ${LIBCXX_INSTALL_PREFIX}bin COMPONENT cxx)
+    LIBRARY DESTINATION ${LIBCXX_INSTALL_LIBRARY_DIR} COMPONENT cxx
+    ARCHIVE DESTINATION ${LIBCXX_INSTALL_LIBRARY_DIR} COMPONENT cxx
+    RUNTIME DESTINATION bin COMPONENT cxx)
 endif()
 
 # NOTE: This install command must go after the cxx install command otherwise
 # it will not be executed after the library symlinks are installed.
 if (LIBCXX_ENABLE_SHARED AND LIBCXX_ENABLE_ABI_LINKER_SCRIPT)
   install(FILES "$<TARGET_LINKER_FILE:cxx_shared>"
-    DESTINATION ${LIBCXX_INSTALL_PREFIX}${LIBCXX_INSTALL_LIBRARY_DIR}
+    DESTINATION ${LIBCXX_INSTALL_LIBRARY_DIR}
     COMPONENT libcxx)
 endif()
 
diff --git a/libcxxabi/CMakeLists.txt b/libcxxabi/CMakeLists.txt
--- a/libcxxabi/CMakeLists.txt
+++ b/libcxxabi/CMakeLists.txt
@@ -211,8 +211,6 @@
   set(LIBCXXABI_INSTALL_LIBRARY_DIR lib${LIBCXXABI_LIBDIR_SUFFIX})
 endif()
 
-set(LIBCXXABI_INSTALL_PREFIX "" CACHE STRING "Define libc++abi destination prefix.")
-
 set(CMAKE_ARCHIVE_OUTPUT_DIRECTORY ${LIBCXXABI_LIBRARY_DIR})
 set(CMAKE_LIBRARY_OUTPUT_DIRECTORY ${LIBCXXABI_LIBRARY_DIR})
 set(CMAKE_RUNTIME_OUTPUT_DIRECTORY ${LIBCXXABI_LIBRARY_DIR})
diff --git a/libcxxabi/src/CMakeLists.txt b/libcxxabi/src/CMakeLists.txt
--- a/libcxxabi/src/CMakeLists.txt
+++ b/libcxxabi/src/CMakeLists.txt
@@ -311,8 +311,8 @@
 
 if (LIBCXXABI_INSTALL_LIBRARY)
   install(TARGETS ${LIBCXXABI_INSTALL_TARGETS}
-    LIBRARY DESTINATION ${LIBCXXABI_INSTALL_PREFIX}${LIBCXXABI_INSTALL_LIBRARY_DIR} COMPONENT cxxabi
-    ARCHIVE DESTINATION ${LIBCXXABI_INSTALL_PREFIX}${LIBCXXABI_INSTALL_LIBRARY_DIR} COMPONENT cxxabi
+    LIBRARY DESTINATION ${LIBCXXABI_INSTALL_LIBRARY_DIR} COMPONENT cxxabi
+    ARCHIVE DESTINATION ${LIBCXXABI_INSTALL_LIBRARY_DIR} COMPONENT cxxabi
     )
 endif()
 
diff --git a/libunwind/CMakeLists.txt b/libunwind/CMakeLists.txt
--- a/libunwind/CMakeLists.txt
+++ b/libunwind/CMakeLists.txt
@@ -133,8 +133,6 @@
 set(CMAKE_LIBRARY_OUTPUT_DIRECTORY ${LIBUNWIND_LIBRARY_DIR})
 set(CMAKE_RUNTIME_OUTPUT_DIRECTORY ${LIBUNWIND_LIBRARY_DIR})
 
-set(LIBUNWIND_INSTALL_PREFIX "" CACHE STRING "Define libunwind destination prefix.")
-
 set(LIBUNWIND_C_FLAGS "")
 set(LIBUNWIND_CXX_FLAGS "")
 set(LIBUNWIND_COMPILE_FLAGS "")
diff --git a/libunwind/src/CMakeLists.txt b/libunwind/src/CMakeLists.txt
--- a/libunwind/src/CMakeLists.txt
+++ b/libunwind/src/CMakeLists.txt
@@ -182,9 +182,9 @@
 
 if (LIBUNWIND_INSTALL_LIBRARY)
   install(TARGETS ${LIBUNWIND_INSTALL_TARGETS}
-    LIBRARY DESTINATION ${LIBUNWIND_INSTALL_PREFIX}${LIBUNWIND_INSTALL_LIBRARY_DIR} COMPONENT unwind
-    ARCHIVE DESTINATION ${LIBUNWIND_INSTALL_PREFIX}${LIBUNWIND_INSTALL_LIBRARY_DIR} COMPONENT unwind
-    RUNTIME DESTINATION ${LIBUNWIND_INSTALL_PREFIX}bin COMPONENT unwind)
+    LIBRARY DESTINATION ${LIBUNWIND_INSTALL_LIBRARY_DIR} COMPONENT unwind
+    ARCHIVE DESTINATION ${LIBUNWIND_INSTALL_LIBRARY_DIR} COMPONENT unwind
+    RUNTIME DESTINATION bin COMPONENT unwind)
 endif()
 
 if (NOT CMAKE_CONFIGURATION_TYPES AND LIBUNWIND_INSTALL_LIBRARY)