diff --git a/llvm/lib/Analysis/InlineCost.cpp b/llvm/lib/Analysis/InlineCost.cpp
--- a/llvm/lib/Analysis/InlineCost.cpp
+++ b/llvm/lib/Analysis/InlineCost.cpp
@@ -672,15 +672,22 @@
   }
 
   bool isCostBenefitAnalysisEnabled() {
-    if (!InlineEnableCostBenefitAnalysis)
-      return false;
-
     if (!PSI || !PSI->hasProfileSummary())
       return false;
 
     if (!GetBFI)
       return false;
 
+    if (InlineEnableCostBenefitAnalysis.getNumOccurrences()) {
+      // Honor the explicit request from the user.
+      if (!InlineEnableCostBenefitAnalysis)
+        return false;
+    } else {
+      // Otherwise, require instrumentation profile.
+      if (!PSI->hasInstrumentationProfile())
+        return false;
+    }
+
     auto *Caller = CandidateCall.getParent()->getParent();
     if (!Caller->getEntryCount())
       return false;