diff --git a/clang/lib/Driver/SanitizerArgs.cpp b/clang/lib/Driver/SanitizerArgs.cpp
--- a/clang/lib/Driver/SanitizerArgs.cpp
+++ b/clang/lib/Driver/SanitizerArgs.cpp
@@ -825,6 +825,12 @@
       AsanInvalidPointerSub = true;
     }
 
+    if (TC.getTriple().isOSDarwin() &&
+        (Args.hasArg(options::OPT_mkernel) ||
+         Args.hasArg(options::OPT_fapple_kext))) {
+      AsanDtorKind = llvm::AsanDtorKind::None;
+    }
+
     if (const auto *Arg =
             Args.getLastArg(options::OPT_sanitize_address_destructor_kind_EQ)) {
       auto parsedAsanDtorKind = AsanDtorKindFromString(Arg->getValue());
diff --git a/clang/test/Driver/darwin-asan-mkernel-kext.c b/clang/test/Driver/darwin-asan-mkernel-kext.c
new file mode 100644
--- /dev/null
+++ b/clang/test/Driver/darwin-asan-mkernel-kext.c
@@ -0,0 +1,15 @@
+// RUN: %clang -target x86_64-apple-darwin10 -fsanitize=address -mkernel -### \
+// RUN:   %s 2>&1 | FileCheck %s
+// RUN: %clang -target x86_64-apple-darwin10 -fsanitize=address -fapple-kext \
+// RUN:   -### %s 2>&1 | FileCheck %s
+// RUN: %clang -target x86_64-apple-darwin10 -fsanitize=address -fapple-kext \
+// RUN:   -mkernel -### %s 2>&1 | FileCheck %s
+
+// CHECK: "-fsanitize-address-destructor-kind=none"
+
+// Check it's possible to override the driver's decision.
+// RUN: %clang -target x86_64-apple-darwin10 -fsanitize=address -fapple-kext \
+// RUN:   -mkernel -### -fsanitize-address-destructor-kind=global %s 2>&1 | \
+// RUN:   FileCheck -check-prefix=CHECK-OVERRIDE %s
+
+// CHECK-OVERRIDE: "-fsanitize-address-destructor-kind=global"