diff --git a/llvm/lib/Transforms/Scalar/MergeICmps.cpp b/llvm/lib/Transforms/Scalar/MergeICmps.cpp
--- a/llvm/lib/Transforms/Scalar/MergeICmps.cpp
+++ b/llvm/lib/Transforms/Scalar/MergeICmps.cpp
@@ -154,6 +154,10 @@
     return {};
   }
   Value *const Addr = LoadI->getOperand(0);
+  if (Addr->getType()->getPointerAddressSpace() != 0) {
+    LLVM_DEBUG(dbgs() << "from non-zero AddressSpace\n");
+    return {};
+  }
   auto *const GEP = dyn_cast<GetElementPtrInst>(Addr);
   if (!GEP)
     return {};
diff --git a/llvm/test/Transforms/MergeICmps/addressspaces.ll b/llvm/test/Transforms/MergeICmps/addressspaces.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/Transforms/MergeICmps/addressspaces.ll
@@ -0,0 +1,67 @@
+; NOTE: Assertions have been autogenerated by utils/update_test_checks.py
+; RUN: opt < %s -mergeicmps -S | FileCheck %s
+
+source_filename = "=="
+target datalayout = "e-m:e-i64:64-n32:64"
+target triple = "powerpc64le-unknown-linux-gnu"
+
+define void @juliaAS([2 x [5 x i64]] addrspace(11)* nocapture nonnull readonly align 8 dereferenceable(80) %0, [2 x [5 x i64]] addrspace(11)* nocapture nonnull readonly align 8 dereferenceable(80) %1) {
+; CHECK-LABEL: @juliaAS(
+; CHECK-NEXT:  top:
+; CHECK-NEXT:    [[TMP2:%.*]] = getelementptr inbounds [2 x [5 x i64]], [2 x [5 x i64]] addrspace(11)* [[TMP0:%.*]], i64 0, i64 1, i64 2
+; CHECK-NEXT:    [[TMP3:%.*]] = getelementptr inbounds [2 x [5 x i64]], [2 x [5 x i64]] addrspace(11)* [[TMP0]], i64 0, i64 1, i64 3
+; CHECK-NEXT:    [[TMP4:%.*]] = getelementptr inbounds [2 x [5 x i64]], [2 x [5 x i64]] addrspace(11)* [[TMP0]], i64 0, i64 1, i64 4
+; CHECK-NEXT:    [[TMP5:%.*]] = getelementptr inbounds [2 x [5 x i64]], [2 x [5 x i64]] addrspace(11)* [[TMP1:%.*]], i64 0, i64 1, i64 2
+; CHECK-NEXT:    [[TMP6:%.*]] = getelementptr inbounds [2 x [5 x i64]], [2 x [5 x i64]] addrspace(11)* [[TMP1]], i64 0, i64 1, i64 3
+; CHECK-NEXT:    [[TMP7:%.*]] = getelementptr inbounds [2 x [5 x i64]], [2 x [5 x i64]] addrspace(11)* [[TMP1]], i64 0, i64 1, i64 4
+; CHECK-NEXT:    [[TMP8:%.*]] = load i64, i64 addrspace(11)* [[TMP2]], align 8
+; CHECK-NEXT:    [[TMP9:%.*]] = load i64, i64 addrspace(11)* [[TMP5]], align 8
+; CHECK-NEXT:    [[DOTNOT17:%.*]] = icmp eq i64 [[TMP8]], [[TMP9]]
+; CHECK-NEXT:    br i1 [[DOTNOT17]], label [[L70:%.*]], label [[L90:%.*]]
+; CHECK:       L70:
+; CHECK-NEXT:    [[TMP10:%.*]] = load i64, i64 addrspace(11)* [[TMP3]], align 8
+; CHECK-NEXT:    [[TMP11:%.*]] = load i64, i64 addrspace(11)* [[TMP6]], align 8
+; CHECK-NEXT:    [[DOTNOT18:%.*]] = icmp eq i64 [[TMP10]], [[TMP11]]
+; CHECK-NEXT:    br i1 [[DOTNOT18]], label [[L74:%.*]], label [[L90]]
+; CHECK:       L74:
+; CHECK-NEXT:    [[TMP12:%.*]] = load i64, i64 addrspace(11)* [[TMP4]], align 8
+; CHECK-NEXT:    [[TMP13:%.*]] = load i64, i64 addrspace(11)* [[TMP7]], align 8
+; CHECK-NEXT:    [[DOTNOT19:%.*]] = icmp eq i64 [[TMP12]], [[TMP13]]
+; CHECK-NEXT:    br label [[L90]]
+; CHECK:       L90:
+; CHECK-NEXT:    [[VALUE_PHI2_OFF0:%.*]] = phi i1 [ false, [[TOP:%.*]] ], [ [[DOTNOT19]], [[L74]] ], [ false, [[L70]] ]
+; CHECK-NEXT:    ret void
+;
+top:
+  %2 = getelementptr inbounds [2 x [5 x i64]], [2 x [5 x i64]] addrspace(11)* %0, i64 0, i64 1, i64 2
+  %3 = getelementptr inbounds [2 x [5 x i64]], [2 x [5 x i64]] addrspace(11)* %0, i64 0, i64 1, i64 3
+  %4 = getelementptr inbounds [2 x [5 x i64]], [2 x [5 x i64]] addrspace(11)* %0, i64 0, i64 1, i64 4
+  %5 = getelementptr inbounds [2 x [5 x i64]], [2 x [5 x i64]] addrspace(11)* %1, i64 0, i64 1, i64 2
+  %6 = getelementptr inbounds [2 x [5 x i64]], [2 x [5 x i64]] addrspace(11)* %1, i64 0, i64 1, i64 3
+  %7 = getelementptr inbounds [2 x [5 x i64]], [2 x [5 x i64]] addrspace(11)* %1, i64 0, i64 1, i64 4
+  %8 = load i64, i64 addrspace(11)* %2, align 8
+  %9 = load i64, i64 addrspace(11)* %5, align 8
+  %.not17 = icmp eq i64 %8, %9
+  br i1 %.not17, label %L70, label %L90
+
+L70:                                              ; preds = %top
+  %10 = load i64, i64 addrspace(11)* %3, align 8
+  %11 = load i64, i64 addrspace(11)* %6, align 8
+  %.not18 = icmp eq i64 %10, %11
+  br i1 %.not18, label %L74, label %L90
+
+L74:                                              ; preds = %L70
+  %12 = load i64, i64 addrspace(11)* %4, align 8
+  %13 = load i64, i64 addrspace(11)* %7, align 8
+  %.not19 = icmp eq i64 %12, %13
+  br label %L90
+
+L90:                                              ; preds = %L74, %L70, %top
+  %value_phi2.off0 = phi i1 [ false, %top ], [ %.not19, %L74 ], [ false, %L70 ]
+  ret void
+}
+
+!llvm.module.flags = !{!0}
+
+!0 = !{i32 1, !"Debug Info Version", i32 3}
+