diff --git a/llvm/lib/Target/PowerPC/PPCMIPeephole.cpp b/llvm/lib/Target/PowerPC/PPCMIPeephole.cpp
--- a/llvm/lib/Target/PowerPC/PPCMIPeephole.cpp
+++ b/llvm/lib/Target/PowerPC/PPCMIPeephole.cpp
@@ -712,7 +712,7 @@
               Simplified = true;
               Register ConvReg1 = RoundInstr->getOperand(1).getReg();
               Register FRSPDefines = RoundInstr->getOperand(0).getReg();
-              MachineInstr &Use = *(MRI->use_instr_begin(FRSPDefines));
+              MachineInstr &Use = *(MRI->use_instr_nodbg_begin(FRSPDefines));
               for (int i = 0, e = Use.getNumOperands(); i < e; ++i)
                 if (Use.getOperand(i).isReg() &&
                     Use.getOperand(i).getReg() == FRSPDefines)
diff --git a/llvm/test/CodeGen/PowerPC/non-debug-mi-search-frspxsrsp.ll b/llvm/test/CodeGen/PowerPC/non-debug-mi-search-frspxsrsp.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/CodeGen/PowerPC/non-debug-mi-search-frspxsrsp.ll
@@ -0,0 +1,96 @@
+; RUN: llc -verify-machineinstrs -mtriple=powerpc64le-unknown-linux-gnu < %s | FileCheck %s
+
+; Function Attrs: nounwind
+define dso_local void @test(float* nocapture readonly %Fptr, <4 x float>* nocapture %Vptr) local_unnamed_addr #0 !dbg !10 {
+; CHECK-LABEL: test:
+; CHECK:       # %bb.0: # %entry
+; CHECK-NEXT:          #DEBUG_VALUE: test:Fptr <- $x3
+; CHECK-NEXT:          #DEBUG_VALUE: test:Vptr <- $x4
+; CHECK-NEXT:          addis 5, 2, .LCPI0_0@toc@ha
+; CHECK-NEXT:  .Ltmp0:
+; CHECK-NEXT:          .loc    1 2 38 prologue_end
+; CHECK-NEXT:          lfsx 0, 0, 3
+; CHECK-NEXT:          addis 3, 2, .LCPI0_1@toc@ha
+; CHECK-NEXT:  .Ltmp1:
+; CHECK-NEXT:          #DEBUG_VALUE: test:Fptr <- $x3
+; CHECK-NEXT:          .loc    1 0 38 is_stmt 0
+; CHECK-NEXT:          lfs 1, .LCPI0_0@toc@l(5)
+; CHECK-NEXT:          lfd 2, .LCPI0_1@toc@l(3)
+; CHECK-NEXT:          .loc    1 2 27
+; CHECK-NEXT:          xssubdp 1, 1, 0
+; CHECK-NEXT:          .loc    1 2 45
+; CHECK-NEXT:          xsadddp 1, 1, 2
+; CHECK-NEXT:  .Ltmp2:
+; CHECK-NEXT:          #DEBUG_VALUE: test:Val <- undef
+; CHECK-NEXT:          .loc    1 0 45
+; CHECK-NEXT:          xxlxor 2, 2, 2
+; CHECK-NEXT:          .loc    1 3 26 is_stmt 1
+; CHECK-NEXT:          xxmrghd 0, 0, 2
+; CHECK-NEXT:          xxmrghd 1, 2, 1
+; CHECK-NEXT:          xvcvdpsp 34, 0
+; CHECK-NEXT:          xvcvdpsp 35, 1
+; CHECK-NEXT:          vmrgew 2, 2, 3
+; CHECK-NEXT:          #DEBUG_VALUE: test:Vptr <- $x4
+; CHECK-NEXT:          .loc    1 3 9 is_stmt 0
+; CHECK-NEXT:          stvx 2, 0, 4
+; CHECK-NEXT:          .loc    1 4 1 is_stmt 1
+; CHECK-NEXT:          blr
+entry:
+  call void @llvm.dbg.value(metadata float* %Fptr, metadata !19, metadata !DIExpression()), !dbg !22
+  call void @llvm.dbg.value(metadata <4 x float>* %Vptr, metadata !20, metadata !DIExpression()), !dbg !22
+  %0 = load float, float* %Fptr, align 4, !dbg !23, !tbaa !24
+  %conv = fpext float %0 to double, !dbg !28
+  %sub = fsub double 1.000000e+00, %conv, !dbg !29
+  %sub1 = fadd double %sub, -4.300000e+00, !dbg !30
+  %conv2 = fptrunc double %sub1 to float, !dbg !31
+  call void @llvm.dbg.value(metadata float %conv2, metadata !21, metadata !DIExpression()), !dbg !22
+  %vecinit4 = insertelement <4 x float> <float poison, float 0.000000e+00, float 0.000000e+00, float poison>, float %conv2, i32 0, !dbg !32
+  %vecinit5 = insertelement <4 x float> %vecinit4, float %0, i32 3, !dbg !32
+  store <4 x float> %vecinit5, <4 x float>* %Vptr, align 16, !dbg !33, !tbaa !34
+  ret void, !dbg !35
+}
+
+declare void @llvm.dbg.value(metadata, metadata, metadata)
+
+attributes #0 = { nounwind }
+
+!llvm.dbg.cu = !{!0}
+!llvm.module.flags = !{!6, !7, !8}
+!llvm.ident = !{!9}
+
+!0 = distinct !DICompileUnit(language: DW_LANG_C99, file: !1, producer: "clang version 12.0.0", isOptimized: true, runtimeVersion: 0, emissionKind: FullDebug, enums: !2, retainedTypes: !3, splitDebugInlining: false, nameTableKind: None)
+!1 = !DIFile(filename: "test.c", directory: "")
+!2 = !{}
+!3 = !{!4, !5}
+!4 = !DIBasicType(name: "float", size: 32, encoding: DW_ATE_float)
+!5 = !DIBasicType(name: "double", size: 64, encoding: DW_ATE_float)
+!6 = !{i32 7, !"Dwarf Version", i32 4}
+!7 = !{i32 2, !"Debug Info Version", i32 3}
+!8 = !{i32 1, !"wchar_size", i32 4}
+!9 = !{!"clang version 12.0.0"}
+!10 = distinct !DISubprogram(name: "test", scope: !1, file: !1, line: 1, type: !11, scopeLine: 1, flags: DIFlagPrototyped | DIFlagAllCallsDescribed, spFlags: DISPFlagDefinition | DISPFlagOptimized, unit: !0, retainedNodes: !18)
+!11 = !DISubroutineType(types: !12)
+!12 = !{null, !13, !14}
+!13 = !DIDerivedType(tag: DW_TAG_pointer_type, baseType: !4, size: 64)
+!14 = !DIDerivedType(tag: DW_TAG_pointer_type, baseType: !15, size: 64)
+!15 = !DICompositeType(tag: DW_TAG_array_type, baseType: !4, size: 128, flags: DIFlagVector, elements: !16)
+!16 = !{!17}
+!17 = !DISubrange(count: 4)
+!18 = !{!19, !20, !21}
+!19 = !DILocalVariable(name: "Fptr", arg: 1, scope: !10, file: !1, line: 1, type: !13)
+!20 = !DILocalVariable(name: "Vptr", arg: 2, scope: !10, file: !1, line: 1, type: !14)
+!21 = !DILocalVariable(name: "Val", scope: !10, file: !1, line: 2, type: !4)
+!22 = !DILocation(line: 0, scope: !10)
+!23 = !DILocation(line: 2, column: 38, scope: !10)
+!24 = !{!25, !25, i64 0}
+!25 = !{!"float", !26, i64 0}
+!26 = !{!"omnipotent char", !27, i64 0}
+!27 = !{!"Simple C/C++ TBAA"}
+!28 = !DILocation(line: 2, column: 29, scope: !10)
+!29 = !DILocation(line: 2, column: 27, scope: !10)
+!30 = !DILocation(line: 2, column: 45, scope: !10)
+!31 = !DILocation(line: 2, column: 15, scope: !10)
+!32 = !DILocation(line: 3, column: 26, scope: !10)
+!33 = !DILocation(line: 3, column: 9, scope: !10)
+!34 = !{!26, !26, i64 0}
+!35 = !DILocation(line: 4, column: 1, scope: !10)