Index: lib/Analysis/ValueTracking.cpp
===================================================================
--- lib/Analysis/ValueTracking.cpp
+++ lib/Analysis/ValueTracking.cpp
@@ -411,6 +411,7 @@
       case Intrinsic::invariant_end:
       case Intrinsic::lifetime_start:
       case Intrinsic::lifetime_end:
+      case Intrinsic::noalias:
       case Intrinsic::objectsize:
       case Intrinsic::ptr_annotation:
       case Intrinsic::var_annotation:
Index: test/Transforms/InstCombine/assume.ll
===================================================================
--- test/Transforms/InstCombine/assume.ll
+++ test/Transforms/InstCombine/assume.ll
@@ -275,6 +275,26 @@
   ret i1 %rval
 }
 
+define i1 @nonnull5(i32** %a) {
+entry:
+  %load = load i32*, i32** %a
+  ;; This call cannot actually trap, and so should not disrupt the assume.
+  %v = call i32* @llvm.noalias.p0i32(i32* %load, metadata !1)
+  %cmp = icmp ne i32* %load, null
+  tail call void @llvm.assume(i1 %cmp)
+  %q = bitcast i32** %a to i32*
+  %rval = icmp eq i32* %v, %q
+  ret i1 %rval
+
+; CHECK-LABEL: @nonnull5
+; CHECK: !nonnull
+; CHECK-NOT: call void @llvm.assume
+}
+
+declare i32* @llvm.noalias.p0i32(i32*, metadata) nounwind
+
+!0 = !{!0, !"some domain"}
+!1 = !{!1, !0, !"some scope"}
 
 attributes #0 = { nounwind uwtable }
 attributes #1 = { nounwind }