diff --git a/clang/lib/CodeGen/CGStmt.cpp b/clang/lib/CodeGen/CGStmt.cpp
--- a/clang/lib/CodeGen/CGStmt.cpp
+++ b/clang/lib/CodeGen/CGStmt.cpp
@@ -2306,8 +2306,21 @@
             std::max((uint64_t)LargestVectorWidth,
                      VT->getPrimitiveSizeInBits().getKnownMinSize());
     } else {
-      ArgTypes.push_back(Dest.getAddress(*this).getType());
-      Args.push_back(Dest.getPointer(*this));
+      llvm::Type *DestAddrTy = Dest.getAddress(*this).getType();
+      llvm::Value *DestPtr = Dest.getPointer(*this);
+      // Matrix types in memory are represented by arrays, but accessed through
+      // vector pointers, with the alignment specified on the access operation.
+      // For inline assembly, update pointer arguments to use vector pointers.
+      // Otherwise there will be a mis-match if the matrix is also an
+      // input-argument which is represented as vector.
+      if (isa<MatrixType>(OutExpr->getType().getCanonicalType())) {
+        DestAddrTy = llvm::PointerType::get(
+            ConvertType(OutExpr->getType()),
+            cast<llvm::PointerType>(DestAddrTy)->getAddressSpace());
+        DestPtr = Builder.CreateBitCast(DestPtr, DestAddrTy);
+      }
+      ArgTypes.push_back(DestAddrTy);
+      Args.push_back(DestPtr);
       Constraints += "=*";
       Constraints += OutputConstraint;
       ReadOnly = ReadNone = false;
diff --git a/clang/test/CodeGen/matrix-type.c b/clang/test/CodeGen/matrix-type.c
--- a/clang/test/CodeGen/matrix-type.c
+++ b/clang/test/CodeGen/matrix-type.c
@@ -162,10 +162,10 @@
   // CHECK-LABEL: define void @matrix_inline_asm_memory_readwrite()
   // CHECK-NEXT:  entry:
   // CHECK-NEXT:    [[ALLOCA:%.+]] = alloca [16 x double], align 8
-  // CHECK-NEXT:    [[PTR:%.+]] = bitcast [16 x double]* [[ALLOCA]] to <16 x double>*
-  // CHECK-NEXT:    [[VAL:%.+]] = load <16 x double>, <16 x double>* [[PTR]], align 8
-  // FIXME: Pointer element type does not match the vector type.
-  // CHECK-NEXT:    call void asm sideeffect "", "=*r|m,0,~{memory},~{dirflag},~{fpsr},~{flags}"([16 x double]* [[ALLOCA]], <16 x double> [[VAL]])
+  // CHECK-NEXT:    [[PTR1:%.+]] = bitcast [16 x double]* [[ALLOCA]] to <16 x double>*
+  // CHECK-NEXT:    [[PTR2:%.+]] = bitcast [16 x double]* [[ALLOCA]] to <16 x double>*
+  // CHECK-NEXT:    [[VAL:%.+]] = load <16 x double>, <16 x double>* [[PTR2]], align 8
+  // CHECK-NEXT:    call void asm sideeffect "", "=*r|m,0,~{memory},~{dirflag},~{fpsr},~{flags}"(<16 x double>* [[PTR1]], <16 x double> [[VAL]])
   // CHECK-NEXT:    ret void
 
   dx4x4_t m;