diff --git a/clang-tools-extra/clang-tidy/readability/SimplifyBooleanExprCheck.cpp b/clang-tools-extra/clang-tidy/readability/SimplifyBooleanExprCheck.cpp
--- a/clang-tools-extra/clang-tidy/readability/SimplifyBooleanExprCheck.cpp
+++ b/clang-tools-extra/clang-tidy/readability/SimplifyBooleanExprCheck.cpp
@@ -422,7 +422,7 @@
                                                   bool Value,
                                                   StringRef BooleanId) {
   Finder->addMatcher(
-      ifStmt(isExpansionInMainFile(),
+      ifStmt(isExpansionInMainFile(), unless(isInTemplateInstantiation()),
              hasCondition(cxxBoolLiteral(equals(Value)).bind(BooleanId)))
           .bind(IfStmtId),
       this);
@@ -433,6 +433,7 @@
                                                   StringRef TernaryId) {
   Finder->addMatcher(
       conditionalOperator(isExpansionInMainFile(),
+                          unless(isInTemplateInstantiation()),
                           hasTrueExpression(cxxBoolLiteral(equals(Value))),
                           hasFalseExpression(cxxBoolLiteral(equals(!Value))))
           .bind(TernaryId),
@@ -443,12 +444,14 @@
                                                   bool Value, StringRef Id) {
   if (ChainedConditionalReturn)
     Finder->addMatcher(ifStmt(isExpansionInMainFile(),
+                              unless(isInTemplateInstantiation()),
                               hasThen(returnsBool(Value, ThenLiteralId)),
                               hasElse(returnsBool(!Value)))
                            .bind(Id),
                        this);
   else
     Finder->addMatcher(ifStmt(isExpansionInMainFile(),
+                              unless(isInTemplateInstantiation()),
                               unless(hasParent(ifStmt())),
                               hasThen(returnsBool(Value, ThenLiteralId)),
                               hasElse(returnsBool(!Value)))
@@ -474,12 +477,16 @@
   auto Else = anyOf(SimpleElse, compoundStmt(statementCountIs(1),
                                              hasAnySubstatement(SimpleElse)));
   if (ChainedConditionalAssignment)
-    Finder->addMatcher(ifStmt(hasThen(Then), hasElse(Else)).bind(Id), this);
+    Finder->addMatcher(ifStmt(unless(isInTemplateInstantiation()),
+                              hasThen(Then), hasElse(Else))
+                           .bind(Id),
+                       this);
   else
-    Finder->addMatcher(
-        ifStmt(unless(hasParent(ifStmt())), hasThen(Then), hasElse(Else))
-            .bind(Id),
-        this);
+    Finder->addMatcher(ifStmt(unless(isInTemplateInstantiation()),
+                              unless(hasParent(ifStmt())), hasThen(Then),
+                              hasElse(Else))
+                           .bind(Id),
+                       this);
 }
 
 void SimplifyBooleanExprCheck::matchCompoundIfReturnsBool(MatchFinder *Finder,
@@ -487,6 +494,7 @@
                                                           StringRef Id) {
   Finder->addMatcher(
       compoundStmt(
+          unless(isInTemplateInstantiation()),
           hasAnySubstatement(
               ifStmt(hasThen(returnsBool(Value)), unless(hasElse(stmt())))),
           hasAnySubstatement(returnStmt(has(ignoringParenImpCasts(
diff --git a/clang-tools-extra/test/clang-tidy/checkers/readability-simplify-bool-expr.cpp b/clang-tools-extra/test/clang-tidy/checkers/readability-simplify-bool-expr.cpp
--- a/clang-tools-extra/test/clang-tidy/checkers/readability-simplify-bool-expr.cpp
+++ b/clang-tools-extra/test/clang-tidy/checkers/readability-simplify-bool-expr.cpp
@@ -948,3 +948,18 @@
 }
 // CHECK-MESSAGES: :[[@LINE-4]]:12: warning: {{.*}} in conditional return
 // CHECK-FIXES: S == (A)S;{{$}}
+
+template <bool B>
+void ignoreInstantiations() {
+  if (B) {
+    return;
+  } else {
+    return;
+  }
+}
+
+void instantiate() {
+  // Just make sure the check isn't fooled by template instantiations.
+  ignoreInstantiations<true>();
+  ignoreInstantiations<false>();
+}