Index: lib/Transforms/Scalar/SROA.cpp
===================================================================
--- lib/Transforms/Scalar/SROA.cpp
+++ lib/Transforms/Scalar/SROA.cpp
@@ -1400,8 +1400,8 @@
   if (Ty == TargetTy)
     return buildGEP(IRB, BasePtr, Indices, NamePrefix);
 
-  // Pointer size to use for the indices.
-  unsigned PtrSize = DL.getPointerTypeSizeInBits(BasePtr->getType());
+  // Offset size to use for the indices.
+  unsigned OffsetSize = DL.getIndexTypeSizeInBits(BasePtr->getType());
 
   // See if we can descend into a struct and locate a field with the correct
   // type.
@@ -1413,7 +1413,7 @@
 
     if (ArrayType *ArrayTy = dyn_cast<ArrayType>(ElementTy)) {
       ElementTy = ArrayTy->getElementType();
-      Indices.push_back(IRB.getIntN(PtrSize, 0));
+      Indices.push_back(IRB.getIntN(OffsetSize, 0));
     } else if (VectorType *VectorTy = dyn_cast<VectorType>(ElementTy)) {
       ElementTy = VectorTy->getElementType();
       Indices.push_back(IRB.getInt32(0));
@@ -2377,7 +2377,7 @@
 #endif
 
     return getAdjustedPtr(IRB, DL, &NewAI,
-                          APInt(DL.getPointerTypeSizeInBits(PointerTy), Offset),
+                          APInt(DL.getIndexTypeSizeInBits(PointerTy), Offset),
                           PointerTy,
 #ifndef NDEBUG
                           Twine(OldName) + "."
@@ -2899,8 +2899,8 @@
     unsigned OtherAS = OtherPtrTy->getPointerAddressSpace();
 
     // Compute the relative offset for the other pointer within the transfer.
-    unsigned IntPtrWidth = DL.getPointerSizeInBits(OtherAS);
-    APInt OtherOffset(IntPtrWidth, NewBeginOffset - BeginOffset);
+    unsigned OffsetWidth = DL.getIndexSizeInBits(OtherAS);
+    APInt OtherOffset(OffsetWidth, NewBeginOffset - BeginOffset);
     unsigned OtherAlign =
       IsDest ? II.getSourceAlignment() : II.getDestAlignment();
     OtherAlign =  MinAlign(OtherAlign ? OtherAlign : 1,
Index: test/Transforms/SROA/pointer-offset-size.ll
===================================================================
--- /dev/null
+++ test/Transforms/SROA/pointer-offset-size.ll
@@ -0,0 +1,19 @@
+; RUN: opt < %s -sroa -S
+target datalayout = "e-p:64:64:64:32"
+
+%struct.test = type { %struct.basic, %struct.basic }
+%struct.basic = type { i16, i8 }
+
+define void @test() {
+entry:
+  %ts2.i = alloca %struct.test
+  %s = alloca %struct.test
+  %0 = bitcast %struct.test* %ts2.i to i8*
+  %1 = bitcast %struct.test* %s to i8*
+  call void @llvm.memcpy.p0i8.p0i8.i32(i8* %0, i8* %1, i32 3, i1 false)
+  %x1.i.i = getelementptr inbounds %struct.test, %struct.test* %ts2.i, i32 0, i32 0, i32 0
+  %2 = load i16, i16* %x1.i.i
+  ret void
+}
+
+declare void @llvm.memcpy.p0i8.p0i8.i32(i8* nocapture writeonly, i8* nocapture readonly, i32, i1)