Index: include/llvm/IR/Metadata.h
===================================================================
--- include/llvm/IR/Metadata.h
+++ include/llvm/IR/Metadata.h
@@ -766,7 +766,7 @@
 
   MDNode(LLVMContext &Context, unsigned ID, StorageType Storage,
          ArrayRef<Metadata *> Ops1, ArrayRef<Metadata *> Ops2 = None);
-  ~MDNode() = default;
+  LLVM_NO_SANITIZE_MEMORY_ATTRIBUTE ~MDNode() = default;
 
   void dropAllReferences();
 
Index: include/llvm/IR/User.h
===================================================================
--- include/llvm/IR/User.h
+++ include/llvm/IR/User.h
@@ -72,8 +72,9 @@
   void growHungoffUses(unsigned N, bool IsPhi = false);
 
 public:
-  ~User() override {
-  }
+  // Repress memory sanitization, due to use-after-destroy by operator
+  // delete. Bug report 24578 identifies this issue.
+  ~User() override {}
   /// \brief Free memory allocated for User and Use objects.
   void operator delete(void *Usr);
   /// \brief Placement delete - required by std, but never called.
Index: include/llvm/Support/Compiler.h
===================================================================
--- include/llvm/Support/Compiler.h
+++ include/llvm/Support/Compiler.h
@@ -323,10 +323,12 @@
 #if __has_feature(memory_sanitizer)
 # define LLVM_MEMORY_SANITIZER_BUILD 1
 # include <sanitizer/msan_interface.h>
+# define LLVM_NO_SANITIZE_MEMORY_ATTRIBUTE __attribute__((no_sanitize_memory))
 #else
 # define LLVM_MEMORY_SANITIZER_BUILD 0
 # define __msan_allocated_memory(p, size)
 # define __msan_unpoison(p, size)
+# define LLVM_NO_SANITIZE_MEMORY_ATTRIBUTE
 #endif
 
 /// \macro LLVM_ADDRESS_SANITIZER_BUILD
Index: lib/IR/User.cpp
===================================================================
--- lib/IR/User.cpp
+++ lib/IR/User.cpp
@@ -118,7 +118,7 @@
 //                         User operator delete Implementation
 //===----------------------------------------------------------------------===//
 
-void User::operator delete(void *Usr) {
+LLVM_NO_SANITIZE_MEMORY_ATTRIBUTE void User::operator delete(void *Usr) {
   // Hung off uses use a single Use* before the User, while other subclasses
   // use a Use[] allocated prior to the user.
   User *Obj = static_cast<User *>(Usr);