diff --git a/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp b/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp
--- a/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp
+++ b/llvm/lib/Transforms/Instrumentation/InstrProfiling.cpp
@@ -997,8 +997,11 @@
         ConstantExpr::getBitCast(ValuesVar, Type::getInt8PtrTy(Ctx));
   }
 
-  if (DebugInfoCorrelate)
+  if (DebugInfoCorrelate) {
+    // Mark the counter variable as used so that it isn't optimized out.
+    CompilerUsedVars.push_back(PD.RegionCounters);
     return PD.RegionCounters;
+  }
 
   // Create data variable.
   auto *IntPtrTy = M->getDataLayout().getIntPtrType(M->getContext());