Index: lib/CodeGen/CGClass.cpp
===================================================================
--- lib/CodeGen/CGClass.cpp
+++ lib/CodeGen/CGClass.cpp
@@ -1448,6 +1448,29 @@
   // Exit the try if applicable.
   if (isTryBody)
     ExitCXXTryStmt(*cast<CXXTryStmt>(Body), true);
+
+  // Insert memory-posioning instrumentation.
+  // Generates function call for handling object poisoning, passing in
+  // references to 'this' and its size as arguments.
+  if (CGM.getCodeGenOpts().SanitizeMemoryUseAfterDtor) {
+    const ASTRecordLayout &Layout =
+        getContext().getASTRecordLayout(Dtor->getParent());
+
+    llvm::Value *Args[2] = {
+      Builder.CreateBitCast(LoadCXXThis(), VoidPtrTy),
+      llvm::ConstantInt::get(CGM.SizeTy, Layout.getSize().getQuantity())
+    };
+    llvm::Type *ArgTypes[2] = {
+      VoidPtrTy,
+      SizeTy
+    };
+
+    llvm::FunctionType *FnType =
+        llvm::FunctionType::get(CGM.VoidTy, ArgTypes, false);
+    llvm::Value *Fn =
+        CGM.CreateRuntimeFunction(FnType, "__sanitizer_dtor_callback");
+    EmitNounwindRuntimeCall(Fn, Args);
+  }
 }
 
 void CodeGenFunction::emitImplicitAssignmentOperatorBody(FunctionArgList &Args) {
Index: test/CodeGenCXX/sanitize-dtor-callback.cpp
===================================================================
--- /dev/null
+++ test/CodeGenCXX/sanitize-dtor-callback.cpp
@@ -0,0 +1,20 @@
+// Test -fsanitize-memory-use-after-dtor
+// RUN: %clang_cc1 -fsanitize=memory -fsanitize-memory-use-after-dtor -triple=x86_64-pc-linux -emit-llvm -o - %s | FileCheck %s
+// RUN: %clang_cc1 -fsanitize=memory -triple=x86_64-pc-linux -emit-llvm -o - %s | FileCheck %s -check-prefix=NO_DTOR_CHECK
+
+struct Simple {
+  int x;
+  ~Simple() {}
+};
+
+int main() {
+  Simple s;
+  s.~Simple();
+}
+// Simple internal member is poisoned by compiler-generated dtor
+// CHECK-LABEL: define linkonce_odr void @_ZN6SimpleD2Ev
+// CHECK: call void @__sanitizer_dtor_callback
+// CHECK: ret void
+
+// NO_DTOR_CHECK-NOT: call void @sanitizer_dtor_callback
+// NO_DTOR_CHECK: ret void